Identification of pyripyropene A as a promising insecticidal compound in a microbial metabolite screening
Approximately 300 microbial natural products in our library were screened for insecticidal activities against three species of agricultural pests, including aphids. Among the several compounds that showed insecticidal activities, pyripyropene A had high aphicidal activity in vivo . Furthermore, in a...
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| Veröffentlicht in: | Journal of antibiotics 2017-03, Vol.70 (3), p.272-276 |
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| container_title | Journal of antibiotics |
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| creator | Horikoshi, Ryo Goto, Kimihiko Mitomi, Masaaki Oyama, Kazuhiko Sunazuka, Toshiaki Ōmura, Satoshi |
| description | Approximately 300 microbial natural products in our library were screened for insecticidal activities against three species of agricultural pests, including aphids. Among the several compounds that showed insecticidal activities, pyripyropene A had high aphicidal activity
in vivo
. Furthermore, in advanced tests, pyripyropene A applications with foliar sprays and soil drenching controlled aphids on cabbage. On the basis of its unique and promising activities, we selected pyripyropene A as the active component of potential insecticides. |
| doi_str_mv | 10.1038/ja.2016.155 |
| format | Article |
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in vivo
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in vivo
. Furthermore, in advanced tests, pyripyropene A applications with foliar sprays and soil drenching controlled aphids on cabbage. 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in vivo
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| subjects | 631/154/1435 631/1647 Animals Aphidoidea Aphids Bacteriology Biomedical and Life Sciences Bioorganic Chemistry Brassica In vivo methods and tests Insecticides Insecticides - toxicity Insects Life Sciences Medicinal Chemistry Metabolites Microbiology Microorganisms Molecular Structure Moths Natural products Organic Chemistry original-article Pests Pyridines - toxicity Sesquiterpenes - toxicity Sprays Tetranychidae |
| title | Identification of pyripyropene A as a promising insecticidal compound in a microbial metabolite screening |
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