Variation in Access to Kidney Transplantation Across Renal Programs in Ontario, Canada

In the United States, kidney transplant rates vary significantly across end‐stage renal disease (ESRD) networks. We conducted a population‐based cohort study to determine whether there was variability in kidney transplant rates across renal programs in a health care system distinct from the United S...

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Veröffentlicht in:American journal of transplantation 2017-06, Vol.17 (6), p.1585-1593
Hauptverfasser: Naylor, K. L., Dixon, S. N., Garg, A. X., Kim, S. J., Blake, P. G., Nesrallah, G. E., McCallum, M. K., D'Antonio, C., Li, A. H., Knoll, G. A.
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container_end_page 1593
container_issue 6
container_start_page 1585
container_title American journal of transplantation
container_volume 17
creator Naylor, K. L.
Dixon, S. N.
Garg, A. X.
Kim, S. J.
Blake, P. G.
Nesrallah, G. E.
McCallum, M. K.
D'Antonio, C.
Li, A. H.
Knoll, G. A.
description In the United States, kidney transplant rates vary significantly across end‐stage renal disease (ESRD) networks. We conducted a population‐based cohort study to determine whether there was variability in kidney transplant rates across renal programs in a health care system distinct from the United States. We included incident chronic dialysis patients in Ontario, Canada, from 2003 to 2013 and determined the 1‐, 5‐, and 10‐year cumulative incidence of kidney transplantation in 27 regional renal programs (similar to U.S. ESRD networks). We also assessed the cumulative incidence of kidney transplant for “healthy” dialysis patients (aged 18–50 years without diabetes, coronary disease, or malignancy). We calculated standardized transplant ratios (STRs) using a Cox proportional hazards model, adjusting for patient characteristics (maximum possible follow‐up of 11 years). Among 23 022 chronic dialysis patients, the 10‐year cumulative incidence of kidney transplantation ranged from 7.4% (95% confidence interval [CI] 4.8–10.7%) to 31.4% (95% CI 16.5–47.5%) across renal programs. Similar variability was observed in our healthy cohort. STRs ranged from 0.3 (95% CI 0.2–0.5) to 1.5 (95% CI 1.4–1.7) across renal programs. There was significant variation in kidney transplant rates across Ontario renal programs despite patients having access to the same publicly funded health care system. A population‐based cohort study finds significant variation in kidney transplant rates across Ontario, Canada, renal programs despite patients having access to the same publicly funded healthcare system.
doi_str_mv 10.1111/ajt.14133
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L. ; Dixon, S. N. ; Garg, A. X. ; Kim, S. J. ; Blake, P. G. ; Nesrallah, G. E. ; McCallum, M. K. ; D'Antonio, C. ; Li, A. H. ; Knoll, G. A.</creator><creatorcontrib>Naylor, K. L. ; Dixon, S. N. ; Garg, A. X. ; Kim, S. J. ; Blake, P. G. ; Nesrallah, G. E. ; McCallum, M. K. ; D'Antonio, C. ; Li, A. H. ; Knoll, G. A.</creatorcontrib><description>In the United States, kidney transplant rates vary significantly across end‐stage renal disease (ESRD) networks. We conducted a population‐based cohort study to determine whether there was variability in kidney transplant rates across renal programs in a health care system distinct from the United States. We included incident chronic dialysis patients in Ontario, Canada, from 2003 to 2013 and determined the 1‐, 5‐, and 10‐year cumulative incidence of kidney transplantation in 27 regional renal programs (similar to U.S. ESRD networks). We also assessed the cumulative incidence of kidney transplant for “healthy” dialysis patients (aged 18–50 years without diabetes, coronary disease, or malignancy). We calculated standardized transplant ratios (STRs) using a Cox proportional hazards model, adjusting for patient characteristics (maximum possible follow‐up of 11 years). Among 23 022 chronic dialysis patients, the 10‐year cumulative incidence of kidney transplantation ranged from 7.4% (95% confidence interval [CI] 4.8–10.7%) to 31.4% (95% CI 16.5–47.5%) across renal programs. Similar variability was observed in our healthy cohort. STRs ranged from 0.3 (95% CI 0.2–0.5) to 1.5 (95% CI 1.4–1.7) across renal programs. There was significant variation in kidney transplant rates across Ontario renal programs despite patients having access to the same publicly funded health care system. 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We included incident chronic dialysis patients in Ontario, Canada, from 2003 to 2013 and determined the 1‐, 5‐, and 10‐year cumulative incidence of kidney transplantation in 27 regional renal programs (similar to U.S. ESRD networks). We also assessed the cumulative incidence of kidney transplant for “healthy” dialysis patients (aged 18–50 years without diabetes, coronary disease, or malignancy). We calculated standardized transplant ratios (STRs) using a Cox proportional hazards model, adjusting for patient characteristics (maximum possible follow‐up of 11 years). Among 23 022 chronic dialysis patients, the 10‐year cumulative incidence of kidney transplantation ranged from 7.4% (95% confidence interval [CI] 4.8–10.7%) to 31.4% (95% CI 16.5–47.5%) across renal programs. Similar variability was observed in our healthy cohort. STRs ranged from 0.3 (95% CI 0.2–0.5) to 1.5 (95% CI 1.4–1.7) across renal programs. There was significant variation in kidney transplant rates across Ontario renal programs despite patients having access to the same publicly funded health care system. 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source MEDLINE; Access via Wiley Online Library; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Adolescent
Adult
Aged
Aged, 80 and over
clinical research/practice
Dialysis
epidemiology
Female
Follow-Up Studies
Glomerular Filtration Rate
Health risk assessment
Health Services Accessibility - statistics & numerical data
Hemodialysis
Humans
Immunology
Kidney Failure, Chronic - surgery
Kidney Function Tests
Kidney transplantation
Kidney Transplantation - methods
kidney transplantation/nephrology
Kidney transplants
Male
Middle Aged
Ontario
Prognosis
quality of care/care delivery
Registries - statistics & numerical data
Renal Dialysis
Retrospective Studies
Risk Factors
Transplants & implants
Young Adult
title Variation in Access to Kidney Transplantation Across Renal Programs in Ontario, Canada
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