Development of a Convenient In Vitro Gel Diffusion Model for Predicting the In Vivo Performance of Subcutaneous Parenteral Formulations of Large and Small Molecules

Parenteral delivery remains a compelling drug delivery route for both large- and small-molecule drugs and can bypass issues encountered with oral absorption. For injectable drug products, there is a strong patient preference for subcutaneous administration due to its convenience over intravenous inf...

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Veröffentlicht in:AAPS PharmSciTech 2017-08, Vol.18 (6), p.2203-2213
Hauptverfasser: Leung, Dennis H., Kapoor, Yash, Alleyne, Candice, Walsh, Erika, Leithead, Andrew, Habulihaz, Bahanu, Salituro, Gino M., Bak, Annette, Rhodes, Timothy
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Sprache:eng
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