Weight loss induced by bariatric surgery restores adipose tissue PNPLA3 expression

Background & Aims Obesity and its related co‐morbidities such as non‐alcoholic fatty liver disease (NAFLD) are increasing dramatically worldwide. The genetic variation in Patatin‐like phospholipase domain‐containing protein 3 (PNPLA3), which is also called adiponutrin (ADPN), in residue 148 (I14...

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Veröffentlicht in:	Liver international 2017-02, Vol.37 (2), p.299-306
Hauptverfasser:	Wieser, Verena, Adolph, Timon E., Enrich, Barbara, Moser, Patrizia, Moschen, Alexander R., Tilg, Herbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes adiponutrin Adipose tissue Adipose Tissue - metabolism Adult Aged Austria Banding Bariatric Surgery Body weight Body weight loss Fasting Fatty liver Female Gastrointestinal surgery Genetic diversity Hepatocytes Hepatocytes - metabolism Humans Inflammation Insulin laparoscopic gastric banding Laparoscopy Lipase - genetics Lipopolysaccharides Liver Liver - pathology Liver diseases Male Membrane Proteins - genetics Metabolic disorders Middle Aged Non-alcoholic Fatty Liver Disease - pathology non‐alcoholic fatty liver disease Obesity Obesity - genetics Obesity - surgery Patatin‐like phospholipase domain‐containing protein 3 Patients Phospholipase Polymerase chain reaction Surgery Tumor necrosis factor Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Tumors Weight Loss Weight reduction Young Adult
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