Regulation of Constitutive and Induced NF- κ B Activation in Malignant Melanoma Cells by Capsaicin Modulates Interleukin-8 Production and Cell Proliferation

In the present study, we demonstrate that upregulation of interleukin-1beta(IL-1beta)-mediated and tumor necrosis factor-alpha (TNF-alpha)-mediated IL-8 expression in human malignant melanoma cells is modulated by the activation of nuclear factor-kappaB (NF-kappaB). Addition of capsaicin (8-methyl-N...

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Veröffentlicht in:	Journal of interferon & cytokine research 2002-04, Vol.22 (4), p.427-435
Hauptverfasser:	Patel, Prabhudas S., Varney, Michelle L., Dave, Bhavana J., Singh, Rakesh K.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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