Probing the Acid-Induced Packing Structure Changes of the Molten Globule Domains of a Protein near Equilibrium Unfolding

Using simultaneously scanning small-angle X-ray scattering (SAXS) and UV–vis absorption with integrated online size exclusion chromatography, supplemental with molecular dynamics simulations, we unveil the long-postulated global structure evolution of a model multidomain protein bovine serum albumin...

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Veröffentlicht in:	The journal of physical chemistry letters 2017-01, Vol.8 (2), p.470-477
Hauptverfasser:	Yeh, Yi-Qi, Liao, Kuei-Fen, Shih, Orion, Shiu, Ying-Jen, Wu, Wei-Ru, Su, Chun-Jen, Lin, Po-Chang, Jeng, U-Ser
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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