Generation of activated and antigen-specific T cells with cytotoxic activity after co-culture with dendritic cells

Co-culturing of immunological effector cells with antigen-pulsed DC leads to an increase of cytotoxic activity against antigen-expressing tumour cells. Using this approach, we could detect up to 2.8% antigen-specific CTLs after co-culture with antigen-pulsed DC. However, the required high effector c...

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Veröffentlicht in:Cancer Immunology, Immunotherapy Immunotherapy, 2002-03, Vol.51 (1), p.33-44
Hauptverfasser: Maerten, A, Greten, T, Ziske, C, Renoth, S, Schoettker, B, Buttgereit, P, Schakowski, F, von Ruecker, A, Sauerbruch, T, Schmidt-Wolf, IGH
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Sprache:eng
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