Specificity of B-Type Natriuretic Peptide Assays: Cross-Reactivity with Different BNP, NT-proBNP, and proBNP Peptides

B-type natriuretic peptides (BNPs) are used clinically to diagnose and monitor heart failure and are present in the circulation as multiple proBNP-derived fragments. We investigated the specificity of BNP immunoassays with glycosylated and nonglycosylated BNP, N-terminal proBNP (NT-proBNP), and proB...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2017-01, Vol.63 (1), p.351-358
Hauptverfasser:	Saenger, Amy K, Rodriguez-Fraga, Olaia, Ler, Ranka, Ordonez-Llanos, Jordi, Jaffe, Allan S, Goetze, Jens Peter, Apple, Fred S
Format:	Artikel
Sprache:	eng
Schlagworte:	Committees Cross Reactions Design Funding Heart failure Humans Immunoassay Immunoassays Immunoglobulins Laboratories Medical research Natriuretic Peptide, Brain - blood Patients Peptides Plasma Regulatory approval Rodents Standardization Studies
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