Helical structures of homo-chiral isotope-labeled α-aminoisobutyric acid peptides

The chiral deuterium- and 13C-isotope-labeled α-aminoisobutyric acids CD3-Aib and 13CH3-Aib were enantioselectively synthesized from L-Ala aldimine using simplified Maruoka chiral phase-transfer catalysts. Homo-chiral (S)-CD3-Aib homopeptides, up to decamers, were prepared. A (R)-CD3-Aib polymer and...

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Veröffentlicht in:	Tetrahedron 2016-09, Vol.72 (39), p.5864-5871
Hauptverfasser:	Ueda, Atsushi, Oba, Makoto, Izumi, Yuki, Sueyoshi, Yasuhito, Doi, Mitsunobu, Demizu, Yosuke, Kurihara, Masaaki, Tanaka, Masakazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aib Catalysis Catalysts Conformation Crystallography Dichroism Helix Peptide Spectra Synthesis (chemistry) Tetrahedrons X-rays α,α-Disubstituted α-amino acid
Online-Zugang:	Volltext
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