Comparison of the specificity and affinity of surface immobilised Affimer binders using the quartz crystal microbalance

To enable multiplexed protein analysis through the use of microarrays, reliable molecules capable of specifically binding to a protein of interest with high affinity are required. Further, this specificity and affinity must be retained upon immobilization to the microarray surface. This study invest...

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Veröffentlicht in:	Analyst (London) 2016-11, Vol.141 (22), p.6278-6286
Hauptverfasser:	Weckman, Nicole E, McRae, Cassey, Ko Ferrigno, Paul, Seshia, Ashwin A
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Animals Binders Binding Biosensing Techniques Immobilized Proteins - chemistry Immunoglobulin G - analysis Mice Microbalances Monitoring Multiplexing Proteins Quartz Crystal Microbalance Techniques Quartz crystals Sensitivity and Specificity
Online-Zugang:	Volltext
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