Linking uterine serous carcinoma to BRCA1/2 -associated cancer syndrome: A meta-analysis and case report

Abstract Background Uterine serous carcinoma (USC) shows greater morphological, clinical and molecular similarities to high-grade ovarian tubal serous carcinoma than to other types of endometrial cancer. As high-grade ovarian tubal serous carcinoma is known to be associated with BRCA1/ 2 pathogenic...

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Veröffentlicht in:	European journal of cancer (1990) 2017-02, Vol.72, p.215-225
Hauptverfasser:	de Jonge, M.M, Mooyaart, A.L, Vreeswijk, M.P.G, de Kroon, C.D, van Wezel, T, van Asperen, C.J, Smit, V.T.H.B.M, Dekkers, O.M, Bosse, T
Format:	Artikel
Sprache:	eng
Schlagworte:	BRCA1 BRCA1 protein BRCA2 Breast Breast cancer Cancer Carcinoma - genetics Case reports Comparative analysis Confidence intervals Deoxyribonucleic acid DNA Endometrial cancer Endometrium Female Genes, BRCA1 Genes, BRCA2 Genetic disorders Genetics Germ-Line Mutation Germline mutation Hematology, Oncology and Palliative Medicine Heterozygosity Homologous recombination Homology Humans Loss of heterozygosity Meta-analysis Middle Aged Minority & ethnic groups Mutation Ovarian cancer Patients Tumors Uterine cancer Uterine Neoplasms - genetics Uterine serous carcinoma Uterus
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