A Preliminary Molecular and Phylogenetic Analysis of the Genome of a Novel Endogenous Retrovirus in the Sea Slug Elysia chlorotica
An endogenous retrovirus that is present in the sea slug Elysia chlorotica is expressed in all individuals at the end of the annual life cycle. But the precise role of the virus, if any, in slug senescence or death is unknown. We have determined the genomic sequence of the virus and performed a phyl...
Gespeichert in:
| Veröffentlicht in: | The Biological bulletin (Lancaster) 2016-12, Vol.231 (3), p.236-244 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 244 |
|---|---|
| container_issue | 3 |
| container_start_page | 236 |
| container_title | The Biological bulletin (Lancaster) |
| container_volume | 231 |
| creator | PIERCE, SIDNEY K. MAHADEVAN, PADMANABHAN MASSEY, STEVEN E. MIDDLEBROOKS, MICHAEL L. |
| description | An endogenous retrovirus that is present in the sea slug Elysia chlorotica is expressed in all individuals at the end of the annual life cycle. But the precise role of the virus, if any, in slug senescence or death is unknown. We have determined the genomic sequence of the virus and performed a phylogenetic analysis of the data. The 6060-base pair genome of the virus possesses a reverse transcriptasedomain-containing protein that shows similarity to retrotransposon sequences found in Aplysia californica and Strongylocentrotus purpuratus. However, nucleotide BLAST analysis of the whole genome resulted in hits to only a few portions of the genome, indicating that the Elysia chlorotica retrovirus is novel, has not been previously sequenced, and does not have great genetic similarity to other known viral species. When more invertebrate retroviral genomes are examined, a more precise phylogenetic placement of the Elysia chlorotica retrovirus can be determined. |
| doi_str_mv | 10.1086/691071 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1855332440</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A492736221</galeid><jstor_id>44134840</jstor_id><sourcerecordid>A492736221</sourcerecordid><originalsourceid>FETCH-LOGICAL-c635t-e4a88b93aa5718c683e5ddd5681ba0f4648d88709bd28a0496a1aad0ce213e503</originalsourceid><addsrcrecordid>eNqN0kFv0zAUB3ALgVgp8A1AlkAIDhl24iTOsapKmVS2icLZcp2XNJUTd3Yy0SufHGcpnYoqVOWQOPr57ye_h9BrSi4p4cnnJKMkpU_QiGZRFvAkS5-iESEkCSLK4wv0wrmNX5KQsufoIuSE8SxmI_R7gm8t6KquGml3-JvRoDotLZZNjm_XO21KaKCtFJ40Uu9c5bApcLsGPIfG1NCvJL4296DxrMl7bTqHv0NrzX1l_WfVPPAlSLzUXYlnfYrEaq2NNT5YvkTPCqkdvNq_x-jnl9mP6ddgcTO_mk4WgUqiuA2ASc5XWSRlnFKuEh5BnOd5nHC6kqRgCeM55ynJVnnIJWFZIqmUOVEQUk9JNEYfh9ytNXcduFbUlVOgtWzA1ywo95mU0_AcGsdRFDLW03f_0I3prL-rB5XEjKYRf1Sl1CCqpjCtlaoPFROWhWmUhL7KMQpOqL4BVmrTQFH530f-8oT3Tw51pU5u-HS0wZsWfrWl7JwTV8vrsy2fL_5X-N4qozWUIHwbpzfH_sPglTXOWSjE1la1H0BBiejnWQzz7OHb_e12qxryA_s7wI-d6tTaz1JpthZ8fYceDDlimxeevj-DevZmYBvXGns4kTEaMe4b_gff4w3I</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1856541738</pqid></control><display><type>article</type><title>A Preliminary Molecular and Phylogenetic Analysis of the Genome of a Novel Endogenous Retrovirus in the Sea Slug Elysia chlorotica</title><source>Jstor Complete Legacy</source><source>MEDLINE</source><creator>PIERCE, SIDNEY K. ; MAHADEVAN, PADMANABHAN ; MASSEY, STEVEN E. ; MIDDLEBROOKS, MICHAEL L.</creator><creatorcontrib>PIERCE, SIDNEY K. ; MAHADEVAN, PADMANABHAN ; MASSEY, STEVEN E. ; MIDDLEBROOKS, MICHAEL L.</creatorcontrib><description>An endogenous retrovirus that is present in the sea slug Elysia chlorotica is expressed in all individuals at the end of the annual life cycle. But the precise role of the virus, if any, in slug senescence or death is unknown. We have determined the genomic sequence of the virus and performed a phylogenetic analysis of the data. The 6060-base pair genome of the virus possesses a reverse transcriptasedomain-containing protein that shows similarity to retrotransposon sequences found in Aplysia californica and Strongylocentrotus purpuratus. However, nucleotide BLAST analysis of the whole genome resulted in hits to only a few portions of the genome, indicating that the Elysia chlorotica retrovirus is novel, has not been previously sequenced, and does not have great genetic similarity to other known viral species. When more invertebrate retroviral genomes are examined, a more precise phylogenetic placement of the Elysia chlorotica retrovirus can be determined.</description><identifier>ISSN: 0006-3185</identifier><identifier>EISSN: 1939-8697</identifier><identifier>DOI: 10.1086/691071</identifier><identifier>PMID: 28048954</identifier><language>eng</language><publisher>United States: Marine Biological Laboratory</publisher><subject>Animals ; Aplysia californica ; Base Sequence ; Elysia chlorotica ; Elysiidae ; Endogenous Retroviruses - classification ; Endogenous Retroviruses - genetics ; Gastropoda - virology ; Genetic aspects ; Genome, Viral - genetics ; Genomes ; Genomics ; Marine ; Mollusks ; Phylogenetics ; Phylogeny ; Proteins ; Retroviridae ; Retroviruses ; Strongylocentrotus purpuratus ; SYMBIOSIS AND PARASITOLOGY ; Viruses</subject><ispartof>The Biological bulletin (Lancaster), 2016-12, Vol.231 (3), p.236-244</ispartof><rights>Copyright © 2016 Marine Biological Laboratory</rights><rights>2016 Marine Biological Laboratory. All rights reserved.</rights><rights>COPYRIGHT 2016 University of Chicago Press</rights><rights>COPYRIGHT 2016 University of Chicago Press</rights><rights>Copyright Marine Biological Laboratory Dec 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c635t-e4a88b93aa5718c683e5ddd5681ba0f4648d88709bd28a0496a1aad0ce213e503</citedby><cites>FETCH-LOGICAL-c635t-e4a88b93aa5718c683e5ddd5681ba0f4648d88709bd28a0496a1aad0ce213e503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44134840$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44134840$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28048954$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PIERCE, SIDNEY K.</creatorcontrib><creatorcontrib>MAHADEVAN, PADMANABHAN</creatorcontrib><creatorcontrib>MASSEY, STEVEN E.</creatorcontrib><creatorcontrib>MIDDLEBROOKS, MICHAEL L.</creatorcontrib><title>A Preliminary Molecular and Phylogenetic Analysis of the Genome of a Novel Endogenous Retrovirus in the Sea Slug Elysia chlorotica</title><title>The Biological bulletin (Lancaster)</title><addtitle>Biol Bull</addtitle><description>An endogenous retrovirus that is present in the sea slug Elysia chlorotica is expressed in all individuals at the end of the annual life cycle. But the precise role of the virus, if any, in slug senescence or death is unknown. We have determined the genomic sequence of the virus and performed a phylogenetic analysis of the data. The 6060-base pair genome of the virus possesses a reverse transcriptasedomain-containing protein that shows similarity to retrotransposon sequences found in Aplysia californica and Strongylocentrotus purpuratus. However, nucleotide BLAST analysis of the whole genome resulted in hits to only a few portions of the genome, indicating that the Elysia chlorotica retrovirus is novel, has not been previously sequenced, and does not have great genetic similarity to other known viral species. When more invertebrate retroviral genomes are examined, a more precise phylogenetic placement of the Elysia chlorotica retrovirus can be determined.</description><subject>Animals</subject><subject>Aplysia californica</subject><subject>Base Sequence</subject><subject>Elysia chlorotica</subject><subject>Elysiidae</subject><subject>Endogenous Retroviruses - classification</subject><subject>Endogenous Retroviruses - genetics</subject><subject>Gastropoda - virology</subject><subject>Genetic aspects</subject><subject>Genome, Viral - genetics</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Marine</subject><subject>Mollusks</subject><subject>Phylogenetics</subject><subject>Phylogeny</subject><subject>Proteins</subject><subject>Retroviridae</subject><subject>Retroviruses</subject><subject>Strongylocentrotus purpuratus</subject><subject>SYMBIOSIS AND PARASITOLOGY</subject><subject>Viruses</subject><issn>0006-3185</issn><issn>1939-8697</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0kFv0zAUB3ALgVgp8A1AlkAIDhl24iTOsapKmVS2icLZcp2XNJUTd3Yy0SufHGcpnYoqVOWQOPr57ye_h9BrSi4p4cnnJKMkpU_QiGZRFvAkS5-iESEkCSLK4wv0wrmNX5KQsufoIuSE8SxmI_R7gm8t6KquGml3-JvRoDotLZZNjm_XO21KaKCtFJ40Uu9c5bApcLsGPIfG1NCvJL4296DxrMl7bTqHv0NrzX1l_WfVPPAlSLzUXYlnfYrEaq2NNT5YvkTPCqkdvNq_x-jnl9mP6ddgcTO_mk4WgUqiuA2ASc5XWSRlnFKuEh5BnOd5nHC6kqRgCeM55ynJVnnIJWFZIqmUOVEQUk9JNEYfh9ytNXcduFbUlVOgtWzA1ywo95mU0_AcGsdRFDLW03f_0I3prL-rB5XEjKYRf1Sl1CCqpjCtlaoPFROWhWmUhL7KMQpOqL4BVmrTQFH530f-8oT3Tw51pU5u-HS0wZsWfrWl7JwTV8vrsy2fL_5X-N4qozWUIHwbpzfH_sPglTXOWSjE1la1H0BBiejnWQzz7OHb_e12qxryA_s7wI-d6tTaz1JpthZ8fYceDDlimxeevj-DevZmYBvXGns4kTEaMe4b_gff4w3I</recordid><startdate>20161201</startdate><enddate>20161201</enddate><creator>PIERCE, SIDNEY K.</creator><creator>MAHADEVAN, PADMANABHAN</creator><creator>MASSEY, STEVEN E.</creator><creator>MIDDLEBROOKS, MICHAEL L.</creator><general>Marine Biological Laboratory</general><general>University of Chicago Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8GL</scope><scope>ISN</scope><scope>7QG</scope><scope>7QP</scope><scope>7QR</scope><scope>7TK</scope><scope>7TN</scope><scope>8FD</scope><scope>F1W</scope><scope>FR3</scope><scope>H95</scope><scope>K9.</scope><scope>L.G</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>7U9</scope><scope>H94</scope></search><sort><creationdate>20161201</creationdate><title>A Preliminary Molecular and Phylogenetic Analysis of the Genome of a Novel Endogenous Retrovirus in the Sea Slug Elysia chlorotica</title><author>PIERCE, SIDNEY K. ; MAHADEVAN, PADMANABHAN ; MASSEY, STEVEN E. ; MIDDLEBROOKS, MICHAEL L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c635t-e4a88b93aa5718c683e5ddd5681ba0f4648d88709bd28a0496a1aad0ce213e503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Animals</topic><topic>Aplysia californica</topic><topic>Base Sequence</topic><topic>Elysia chlorotica</topic><topic>Elysiidae</topic><topic>Endogenous Retroviruses - classification</topic><topic>Endogenous Retroviruses - genetics</topic><topic>Gastropoda - virology</topic><topic>Genetic aspects</topic><topic>Genome, Viral - genetics</topic><topic>Genomes</topic><topic>Genomics</topic><topic>Marine</topic><topic>Mollusks</topic><topic>Phylogenetics</topic><topic>Phylogeny</topic><topic>Proteins</topic><topic>Retroviridae</topic><topic>Retroviruses</topic><topic>Strongylocentrotus purpuratus</topic><topic>SYMBIOSIS AND PARASITOLOGY</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PIERCE, SIDNEY K.</creatorcontrib><creatorcontrib>MAHADEVAN, PADMANABHAN</creatorcontrib><creatorcontrib>MASSEY, STEVEN E.</creatorcontrib><creatorcontrib>MIDDLEBROOKS, MICHAEL L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: High School</collection><collection>Gale In Context: Canada</collection><collection>Animal Behavior Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Technology Research Database</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>The Biological bulletin (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PIERCE, SIDNEY K.</au><au>MAHADEVAN, PADMANABHAN</au><au>MASSEY, STEVEN E.</au><au>MIDDLEBROOKS, MICHAEL L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Preliminary Molecular and Phylogenetic Analysis of the Genome of a Novel Endogenous Retrovirus in the Sea Slug Elysia chlorotica</atitle><jtitle>The Biological bulletin (Lancaster)</jtitle><addtitle>Biol Bull</addtitle><date>2016-12-01</date><risdate>2016</risdate><volume>231</volume><issue>3</issue><spage>236</spage><epage>244</epage><pages>236-244</pages><issn>0006-3185</issn><eissn>1939-8697</eissn><abstract>An endogenous retrovirus that is present in the sea slug Elysia chlorotica is expressed in all individuals at the end of the annual life cycle. But the precise role of the virus, if any, in slug senescence or death is unknown. We have determined the genomic sequence of the virus and performed a phylogenetic analysis of the data. The 6060-base pair genome of the virus possesses a reverse transcriptasedomain-containing protein that shows similarity to retrotransposon sequences found in Aplysia californica and Strongylocentrotus purpuratus. However, nucleotide BLAST analysis of the whole genome resulted in hits to only a few portions of the genome, indicating that the Elysia chlorotica retrovirus is novel, has not been previously sequenced, and does not have great genetic similarity to other known viral species. When more invertebrate retroviral genomes are examined, a more precise phylogenetic placement of the Elysia chlorotica retrovirus can be determined.</abstract><cop>United States</cop><pub>Marine Biological Laboratory</pub><pmid>28048954</pmid><doi>10.1086/691071</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-3185 |
| ispartof | The Biological bulletin (Lancaster), 2016-12, Vol.231 (3), p.236-244 |
| issn | 0006-3185 1939-8697 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1855332440 |
| source | Jstor Complete Legacy; MEDLINE |
| subjects | Animals Aplysia californica Base Sequence Elysia chlorotica Elysiidae Endogenous Retroviruses - classification Endogenous Retroviruses - genetics Gastropoda - virology Genetic aspects Genome, Viral - genetics Genomes Genomics Marine Mollusks Phylogenetics Phylogeny Proteins Retroviridae Retroviruses Strongylocentrotus purpuratus SYMBIOSIS AND PARASITOLOGY Viruses |
| title | A Preliminary Molecular and Phylogenetic Analysis of the Genome of a Novel Endogenous Retrovirus in the Sea Slug Elysia chlorotica |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T21%3A17%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Preliminary%20Molecular%20and%20Phylogenetic%20Analysis%20of%20the%20Genome%20of%20a%20Novel%20Endogenous%20Retrovirus%20in%20the%20Sea%20Slug%20Elysia%20chlorotica&rft.jtitle=The%20Biological%20bulletin%20(Lancaster)&rft.au=PIERCE,%20SIDNEY%20K.&rft.date=2016-12-01&rft.volume=231&rft.issue=3&rft.spage=236&rft.epage=244&rft.pages=236-244&rft.issn=0006-3185&rft.eissn=1939-8697&rft_id=info:doi/10.1086/691071&rft_dat=%3Cgale_proqu%3EA492736221%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1856541738&rft_id=info:pmid/28048954&rft_galeid=A492736221&rft_jstor_id=44134840&rfr_iscdi=true |