Efficacy and Safety of Endovascular Therapy for Aortoiliac TASC D Lesions

Background: Although there is increasing evidence of the effectiveness of endovascular therapy for complex aortoiliac (AI) occlusive disease, it is not universally applied to TASC D lesions. Methods: A total of 2096 patients, 2601 limbs with AI occlusive disease, were enrolled. The lesions were cate...

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Veröffentlicht in:Angiology 2017-01, Vol.68 (1), p.67-73
Hauptverfasser: Suzuki, Kenji, Mizutani, Yukiko, Soga, Yoshimitsu, Iida, Osamu, Kawasaki, Daizo, Yamauchi, Yasutaka, Hirano, Keisuke, Koshida, Ryouji, Kamoi, Daisuke, Tazaki, Junichi, Higashitani, Michiaki, Shintani, Yoshiaki, Yamaoka, Terutoshi, Okazaki, Shinya, Suematsu, Nobuhiro, Tsuchiya, Taketsugu, Miyashita, Yusuke, Shinozaki, Norihiko, Takahashi, Hiroki, Inoue, Naoto
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container_end_page 73
container_issue 1
container_start_page 67
container_title Angiology
container_volume 68
creator Suzuki, Kenji
Mizutani, Yukiko
Soga, Yoshimitsu
Iida, Osamu
Kawasaki, Daizo
Yamauchi, Yasutaka
Hirano, Keisuke
Koshida, Ryouji
Kamoi, Daisuke
Tazaki, Junichi
Higashitani, Michiaki
Shintani, Yoshiaki
Yamaoka, Terutoshi
Okazaki, Shinya
Suematsu, Nobuhiro
Tsuchiya, Taketsugu
Miyashita, Yusuke
Shinozaki, Norihiko
Takahashi, Hiroki
Inoue, Naoto
description Background: Although there is increasing evidence of the effectiveness of endovascular therapy for complex aortoiliac (AI) occlusive disease, it is not universally applied to TASC D lesions. Methods: A total of 2096 patients, 2601 limbs with AI occlusive disease, were enrolled. The lesions were categorized as TASC D (395) or TASC A-C (2206), and we compared baseline data, procedure, and follow-up result between the 2 groups. Results: The success rate of the procedure was significantly lower in the TASC D group (91.6% vs 99.3%, P < .01), and more procedure complications occurred in the TASC D group (11.1% vs 5.2%, P < .01). The results of a 5-year follow-up revealed no significant difference in primary patency (77.9% vs 77.1%, P = .17) and major adverse cardiovascular and limb events (MACLE; 30.5% vs 33.4%, P = .42) between the 2 groups. A multivariate analysis revealed complications and critical limb ischemia are independent predictors of MACLE in the TASC D group. Conclusion: The success rate of the procedure was lower in the TASC D group. Complications were more frequent in the TASC D group, and they were related to MACLE.
doi_str_mv 10.1177/0003319716638005
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Methods: A total of 2096 patients, 2601 limbs with AI occlusive disease, were enrolled. The lesions were categorized as TASC D (395) or TASC A-C (2206), and we compared baseline data, procedure, and follow-up result between the 2 groups. Results: The success rate of the procedure was significantly lower in the TASC D group (91.6% vs 99.3%, P &lt; .01), and more procedure complications occurred in the TASC D group (11.1% vs 5.2%, P &lt; .01). The results of a 5-year follow-up revealed no significant difference in primary patency (77.9% vs 77.1%, P = .17) and major adverse cardiovascular and limb events (MACLE; 30.5% vs 33.4%, P = .42) between the 2 groups. A multivariate analysis revealed complications and critical limb ischemia are independent predictors of MACLE in the TASC D group. Conclusion: The success rate of the procedure was lower in the TASC D group. Complications were more frequent in the TASC D group, and they were related to MACLE.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>26980775</pmid><doi>10.1177/0003319716638005</doi><tpages>7</tpages></addata></record>
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subjects Aged
Angioplasty, Balloon - adverse effects
Angioplasty, Balloon - methods
Arterial Occlusive Diseases - physiopathology
Arterial Occlusive Diseases - surgery
Endovascular Procedures - adverse effects
Female
Femoral Artery - surgery
Humans
Iliac Artery - physiopathology
Iliac Artery - surgery
Male
Middle Aged
Peripheral Arterial Disease - physiopathology
Peripheral Arterial Disease - surgery
Prosthesis Design
Risk Factors
Treatment Outcome
Vascular Patency - physiology
title Efficacy and Safety of Endovascular Therapy for Aortoiliac TASC D Lesions
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