The prevalence, natural history and time trends of peanut allergy over the first 10 years of life in two cohorts born in the same geographical location 12 years apart
Background The aim of this study was to explore the natural history of peanut allergy in childhood in two birth cohorts from the same geographical region in the South of England. Methods The FAIR birth cohort was established on the Isle of Wight (UK) between 2001 and 2002 (n = 969). Children were fo...
Gespeichert in:
| Veröffentlicht in: | Pediatric allergy and immunology 2016-12, Vol.27 (8), p.804-811 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 811 |
|---|---|
| container_issue | 8 |
| container_start_page | 804 |
| container_title | Pediatric allergy and immunology |
| container_volume | 27 |
| creator | Venter, Carina Maslin, Kate Patil, Veeresh Kurukulaaratchy, Ramesh Grundy, Jane Glasbey, Gillian Twiselton, Roger Dean, Taraneh Arshad, Syed Hasan |
| description | Background
The aim of this study was to explore the natural history of peanut allergy in childhood in two birth cohorts from the same geographical region in the South of England.
Methods
The FAIR birth cohort was established on the Isle of Wight (UK) between 2001 and 2002 (n = 969). Children were followed up prospectively, skin prick tested (SPT) to peanut allergens at 1, 2, 3 and 10 years and food challenges performed. The Isle of Wight (IOW) birth cohort was established in 1989 (n = 1456). SPTs were performed at 1, 2, 4 and 10 years. Peanut allergy was based on positive SPT and a good clinical history.
Results
In the FAIR cohort, the prevalence of sensitization to peanut was 0.4%, 2.0%, 2.0% and 2.4% at 1, 2, 3 and 10 years, respectively. At 10 years of age, 12 of 828 (1.5%) children were diagnosed with peanut allergy. One child (8%) outgrew her peanut allergy between 3 and 10 years and two children (15%) presented with new onset peanut allergy. Over the first 10 years of life, 13 of 934 (1.4%) children were diagnosed with peanut allergy. In the IOW cohort, 6 of 1034 (0.58%) were diagnosed with peanut allergy at 10 years. We found no significant differences between the FAIR and the IOW birth cohort for any of the time points studied.
Conclusion
Peanut allergy appears to be stable over the first 10 years of life in our cohorts. There was no significant difference in peanut sensitization or clinical peanut allergy between 1989 and 2001. |
| doi_str_mv | 10.1111/pai.12616 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1855077690</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1855077690</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4596-5691a00614b2cb3bbcedf3b4bed52887627261157bbb76c7e47abbca1a0d0b043</originalsourceid><addsrcrecordid>eNqNkc1u1DAURi0EokNhwQsgS2xAIq1_EjtZVgWGSlVhUWBp2c7NjEsmDrbTkrdhyXPwZLgznS6QkPDGknW-c-X7IfSckiOaz_Go3RFlgooHaEF50xSc8PohWpCGVIWglTxAT2K8IoRKLuhjdMBkyUtO2QL9ulwDHgNc6x4GC2_woNMUdI_XLiYfZqyHFie3AZwCDG3EvsMj6GFKWPc9hNWM_TUEnLKmcyEmTMnvnzPosEV71wF2A043Hlu_9iFFbHwYtm85EnU2r8Cvgh7Xzua5vbc6OT9gyvYePeqQnqJHne4jPLu7D9Hn9-8uTz8U5x-XZ6cn54Utq0YUlWioJkTQ0jBruDEW2o6b0kBbsbqWgsm8qLwSY4wUVkIpdYZ0DrXEkJIfolc77xj89wliUhsXLfS9HsBPUdG6qoiUoiH_gTIhWcNKkdGXf6FXfgpD_kimSlE1VLDb2a93lA0-xgCdGoPb6DArStRt0yo3rbZNZ_bFnXEyG2jvyX21GTjeATeuh_nfJvXp5GyvLHaJXD38uE_o8E0JyWWlvl4s1cUXWS_fEq4k_wPecsO5</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1846591624</pqid></control><display><type>article</type><title>The prevalence, natural history and time trends of peanut allergy over the first 10 years of life in two cohorts born in the same geographical location 12 years apart</title><source>Wiley-Blackwell Journals</source><source>MEDLINE</source><creator>Venter, Carina ; Maslin, Kate ; Patil, Veeresh ; Kurukulaaratchy, Ramesh ; Grundy, Jane ; Glasbey, Gillian ; Twiselton, Roger ; Dean, Taraneh ; Arshad, Syed Hasan</creator><creatorcontrib>Venter, Carina ; Maslin, Kate ; Patil, Veeresh ; Kurukulaaratchy, Ramesh ; Grundy, Jane ; Glasbey, Gillian ; Twiselton, Roger ; Dean, Taraneh ; Arshad, Syed Hasan</creatorcontrib><description>Background
The aim of this study was to explore the natural history of peanut allergy in childhood in two birth cohorts from the same geographical region in the South of England.
Methods
The FAIR birth cohort was established on the Isle of Wight (UK) between 2001 and 2002 (n = 969). Children were followed up prospectively, skin prick tested (SPT) to peanut allergens at 1, 2, 3 and 10 years and food challenges performed. The Isle of Wight (IOW) birth cohort was established in 1989 (n = 1456). SPTs were performed at 1, 2, 4 and 10 years. Peanut allergy was based on positive SPT and a good clinical history.
Results
In the FAIR cohort, the prevalence of sensitization to peanut was 0.4%, 2.0%, 2.0% and 2.4% at 1, 2, 3 and 10 years, respectively. At 10 years of age, 12 of 828 (1.5%) children were diagnosed with peanut allergy. One child (8%) outgrew her peanut allergy between 3 and 10 years and two children (15%) presented with new onset peanut allergy. Over the first 10 years of life, 13 of 934 (1.4%) children were diagnosed with peanut allergy. In the IOW cohort, 6 of 1034 (0.58%) were diagnosed with peanut allergy at 10 years. We found no significant differences between the FAIR and the IOW birth cohort for any of the time points studied.
Conclusion
Peanut allergy appears to be stable over the first 10 years of life in our cohorts. There was no significant difference in peanut sensitization or clinical peanut allergy between 1989 and 2001.</description><identifier>ISSN: 0905-6157</identifier><identifier>EISSN: 1399-3038</identifier><identifier>DOI: 10.1111/pai.12616</identifier><identifier>PMID: 27434312</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Allergens - immunology ; Arachis - immunology ; birth cohort ; Child ; Child, Preschool ; Cohort Studies ; Epidemiology ; Female ; Food allergies ; food allergy epidemiology ; Humans ; Immunoglobulin E - metabolism ; Infant ; Infant, Newborn ; Male ; Medical History Taking ; peanut allergy ; Peanut Hypersensitivity - epidemiology ; Peanuts ; Pediatrics ; Prevalence ; Prospective Studies ; Skin Tests ; Time Factors ; time trends ; United Kingdom - epidemiology</subject><ispartof>Pediatric allergy and immunology, 2016-12, Vol.27 (8), p.804-811</ispartof><rights>2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><rights>2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2016 John Wiley & Sons A/S</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4596-5691a00614b2cb3bbcedf3b4bed52887627261157bbb76c7e47abbca1a0d0b043</citedby><cites>FETCH-LOGICAL-c4596-5691a00614b2cb3bbcedf3b4bed52887627261157bbb76c7e47abbca1a0d0b043</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fpai.12616$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fpai.12616$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27434312$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Venter, Carina</creatorcontrib><creatorcontrib>Maslin, Kate</creatorcontrib><creatorcontrib>Patil, Veeresh</creatorcontrib><creatorcontrib>Kurukulaaratchy, Ramesh</creatorcontrib><creatorcontrib>Grundy, Jane</creatorcontrib><creatorcontrib>Glasbey, Gillian</creatorcontrib><creatorcontrib>Twiselton, Roger</creatorcontrib><creatorcontrib>Dean, Taraneh</creatorcontrib><creatorcontrib>Arshad, Syed Hasan</creatorcontrib><title>The prevalence, natural history and time trends of peanut allergy over the first 10 years of life in two cohorts born in the same geographical location 12 years apart</title><title>Pediatric allergy and immunology</title><addtitle>Pediatr Allergy Immunol</addtitle><description>Background
The aim of this study was to explore the natural history of peanut allergy in childhood in two birth cohorts from the same geographical region in the South of England.
Methods
The FAIR birth cohort was established on the Isle of Wight (UK) between 2001 and 2002 (n = 969). Children were followed up prospectively, skin prick tested (SPT) to peanut allergens at 1, 2, 3 and 10 years and food challenges performed. The Isle of Wight (IOW) birth cohort was established in 1989 (n = 1456). SPTs were performed at 1, 2, 4 and 10 years. Peanut allergy was based on positive SPT and a good clinical history.
Results
In the FAIR cohort, the prevalence of sensitization to peanut was 0.4%, 2.0%, 2.0% and 2.4% at 1, 2, 3 and 10 years, respectively. At 10 years of age, 12 of 828 (1.5%) children were diagnosed with peanut allergy. One child (8%) outgrew her peanut allergy between 3 and 10 years and two children (15%) presented with new onset peanut allergy. Over the first 10 years of life, 13 of 934 (1.4%) children were diagnosed with peanut allergy. In the IOW cohort, 6 of 1034 (0.58%) were diagnosed with peanut allergy at 10 years. We found no significant differences between the FAIR and the IOW birth cohort for any of the time points studied.
Conclusion
Peanut allergy appears to be stable over the first 10 years of life in our cohorts. There was no significant difference in peanut sensitization or clinical peanut allergy between 1989 and 2001.</description><subject>Allergens - immunology</subject><subject>Arachis - immunology</subject><subject>birth cohort</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cohort Studies</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Food allergies</subject><subject>food allergy epidemiology</subject><subject>Humans</subject><subject>Immunoglobulin E - metabolism</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medical History Taking</subject><subject>peanut allergy</subject><subject>Peanut Hypersensitivity - epidemiology</subject><subject>Peanuts</subject><subject>Pediatrics</subject><subject>Prevalence</subject><subject>Prospective Studies</subject><subject>Skin Tests</subject><subject>Time Factors</subject><subject>time trends</subject><subject>United Kingdom - epidemiology</subject><issn>0905-6157</issn><issn>1399-3038</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc1u1DAURi0EokNhwQsgS2xAIq1_EjtZVgWGSlVhUWBp2c7NjEsmDrbTkrdhyXPwZLgznS6QkPDGknW-c-X7IfSckiOaz_Go3RFlgooHaEF50xSc8PohWpCGVIWglTxAT2K8IoRKLuhjdMBkyUtO2QL9ulwDHgNc6x4GC2_woNMUdI_XLiYfZqyHFie3AZwCDG3EvsMj6GFKWPc9hNWM_TUEnLKmcyEmTMnvnzPosEV71wF2A043Hlu_9iFFbHwYtm85EnU2r8Cvgh7Xzua5vbc6OT9gyvYePeqQnqJHne4jPLu7D9Hn9-8uTz8U5x-XZ6cn54Utq0YUlWioJkTQ0jBruDEW2o6b0kBbsbqWgsm8qLwSY4wUVkIpdYZ0DrXEkJIfolc77xj89wliUhsXLfS9HsBPUdG6qoiUoiH_gTIhWcNKkdGXf6FXfgpD_kimSlE1VLDb2a93lA0-xgCdGoPb6DArStRt0yo3rbZNZ_bFnXEyG2jvyX21GTjeATeuh_nfJvXp5GyvLHaJXD38uE_o8E0JyWWlvl4s1cUXWS_fEq4k_wPecsO5</recordid><startdate>201612</startdate><enddate>201612</enddate><creator>Venter, Carina</creator><creator>Maslin, Kate</creator><creator>Patil, Veeresh</creator><creator>Kurukulaaratchy, Ramesh</creator><creator>Grundy, Jane</creator><creator>Glasbey, Gillian</creator><creator>Twiselton, Roger</creator><creator>Dean, Taraneh</creator><creator>Arshad, Syed Hasan</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201612</creationdate><title>The prevalence, natural history and time trends of peanut allergy over the first 10 years of life in two cohorts born in the same geographical location 12 years apart</title><author>Venter, Carina ; Maslin, Kate ; Patil, Veeresh ; Kurukulaaratchy, Ramesh ; Grundy, Jane ; Glasbey, Gillian ; Twiselton, Roger ; Dean, Taraneh ; Arshad, Syed Hasan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4596-5691a00614b2cb3bbcedf3b4bed52887627261157bbb76c7e47abbca1a0d0b043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Allergens - immunology</topic><topic>Arachis - immunology</topic><topic>birth cohort</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cohort Studies</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Food allergies</topic><topic>food allergy epidemiology</topic><topic>Humans</topic><topic>Immunoglobulin E - metabolism</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Medical History Taking</topic><topic>peanut allergy</topic><topic>Peanut Hypersensitivity - epidemiology</topic><topic>Peanuts</topic><topic>Pediatrics</topic><topic>Prevalence</topic><topic>Prospective Studies</topic><topic>Skin Tests</topic><topic>Time Factors</topic><topic>time trends</topic><topic>United Kingdom - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Venter, Carina</creatorcontrib><creatorcontrib>Maslin, Kate</creatorcontrib><creatorcontrib>Patil, Veeresh</creatorcontrib><creatorcontrib>Kurukulaaratchy, Ramesh</creatorcontrib><creatorcontrib>Grundy, Jane</creatorcontrib><creatorcontrib>Glasbey, Gillian</creatorcontrib><creatorcontrib>Twiselton, Roger</creatorcontrib><creatorcontrib>Dean, Taraneh</creatorcontrib><creatorcontrib>Arshad, Syed Hasan</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric allergy and immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Venter, Carina</au><au>Maslin, Kate</au><au>Patil, Veeresh</au><au>Kurukulaaratchy, Ramesh</au><au>Grundy, Jane</au><au>Glasbey, Gillian</au><au>Twiselton, Roger</au><au>Dean, Taraneh</au><au>Arshad, Syed Hasan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence, natural history and time trends of peanut allergy over the first 10 years of life in two cohorts born in the same geographical location 12 years apart</atitle><jtitle>Pediatric allergy and immunology</jtitle><addtitle>Pediatr Allergy Immunol</addtitle><date>2016-12</date><risdate>2016</risdate><volume>27</volume><issue>8</issue><spage>804</spage><epage>811</epage><pages>804-811</pages><issn>0905-6157</issn><eissn>1399-3038</eissn><abstract>Background
The aim of this study was to explore the natural history of peanut allergy in childhood in two birth cohorts from the same geographical region in the South of England.
Methods
The FAIR birth cohort was established on the Isle of Wight (UK) between 2001 and 2002 (n = 969). Children were followed up prospectively, skin prick tested (SPT) to peanut allergens at 1, 2, 3 and 10 years and food challenges performed. The Isle of Wight (IOW) birth cohort was established in 1989 (n = 1456). SPTs were performed at 1, 2, 4 and 10 years. Peanut allergy was based on positive SPT and a good clinical history.
Results
In the FAIR cohort, the prevalence of sensitization to peanut was 0.4%, 2.0%, 2.0% and 2.4% at 1, 2, 3 and 10 years, respectively. At 10 years of age, 12 of 828 (1.5%) children were diagnosed with peanut allergy. One child (8%) outgrew her peanut allergy between 3 and 10 years and two children (15%) presented with new onset peanut allergy. Over the first 10 years of life, 13 of 934 (1.4%) children were diagnosed with peanut allergy. In the IOW cohort, 6 of 1034 (0.58%) were diagnosed with peanut allergy at 10 years. We found no significant differences between the FAIR and the IOW birth cohort for any of the time points studied.
Conclusion
Peanut allergy appears to be stable over the first 10 years of life in our cohorts. There was no significant difference in peanut sensitization or clinical peanut allergy between 1989 and 2001.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>27434312</pmid><doi>10.1111/pai.12616</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0905-6157 |
| ispartof | Pediatric allergy and immunology, 2016-12, Vol.27 (8), p.804-811 |
| issn | 0905-6157 1399-3038 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1855077690 |
| source | Wiley-Blackwell Journals; MEDLINE |
| subjects | Allergens - immunology Arachis - immunology birth cohort Child Child, Preschool Cohort Studies Epidemiology Female Food allergies food allergy epidemiology Humans Immunoglobulin E - metabolism Infant Infant, Newborn Male Medical History Taking peanut allergy Peanut Hypersensitivity - epidemiology Peanuts Pediatrics Prevalence Prospective Studies Skin Tests Time Factors time trends United Kingdom - epidemiology |
| title | The prevalence, natural history and time trends of peanut allergy over the first 10 years of life in two cohorts born in the same geographical location 12 years apart |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-04T14%3A27%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20prevalence,%20natural%20history%20and%20time%20trends%20of%20peanut%20allergy%20over%20the%20first%2010%C2%A0years%20of%20life%20in%20two%20cohorts%20born%20in%20the%20same%20geographical%20location%2012%C2%A0years%20apart&rft.jtitle=Pediatric%20allergy%20and%20immunology&rft.au=Venter,%20Carina&rft.date=2016-12&rft.volume=27&rft.issue=8&rft.spage=804&rft.epage=811&rft.pages=804-811&rft.issn=0905-6157&rft.eissn=1399-3038&rft_id=info:doi/10.1111/pai.12616&rft_dat=%3Cproquest_cross%3E1855077690%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1846591624&rft_id=info:pmid/27434312&rfr_iscdi=true |