Interactions of Bimodal Magnetic and Fluorescent Nanoparticles Based on Carbon Quantum Dots and Iron-Carbon Nanocomposites with Cell Cultures
Interactions of bimodal (fluorescent and magnetic) nanoparticles with HeLa cells were studied. The nanoparticles, characterized by high magnetic moment and relaxing capacity, exhibited fluorescence sufficient for their use as labels in confocal microscopy and flow cytometry. Penetration of these nan...
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2016-12, Vol.162 (2), p.248-251 |
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description | Interactions of bimodal (fluorescent and magnetic) nanoparticles with HeLa cells were studied. The nanoparticles, characterized by high magnetic moment and relaxing capacity, exhibited fluorescence sufficient for their use as labels in confocal microscopy and flow cytometry. Penetration of these nanoparticles into the cell depended on their surface charge: positively charged nanoparticles of this structure penetrated inside, while negatively charged particles were not found in the cells. |
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subjects | Biological Transport Biomedical and Life Sciences Biomedicine Biotechnologies Carbon - chemistry Cell Biology Cell Membrane Permeability Cell Survival Charged particles Confocal microscopy Flow Cytometry Fluorescent Dyes - chemistry Fluorescent Dyes - metabolism HeLa Cells Humans Internal Medicine Iron Iron - chemistry Laboratory Medicine Magnetite Nanoparticles - chemistry Microscopy, Confocal Nanocomposites Nanocomposites - chemistry Nanoparticles Pathology Quantum dots Quantum Dots - chemistry Quantum Dots - metabolism Static Electricity Surface charge Surface Properties |
title | Interactions of Bimodal Magnetic and Fluorescent Nanoparticles Based on Carbon Quantum Dots and Iron-Carbon Nanocomposites with Cell Cultures |
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