Interactions of Bimodal Magnetic and Fluorescent Nanoparticles Based on Carbon Quantum Dots and Iron-Carbon Nanocomposites with Cell Cultures

Interactions of bimodal (fluorescent and magnetic) nanoparticles with HeLa cells were studied. The nanoparticles, characterized by high magnetic moment and relaxing capacity, exhibited fluorescence sufficient for their use as labels in confocal microscopy and flow cytometry. Penetration of these nan...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2016-12, Vol.162 (2), p.248-251
Hauptverfasser: Minin, A. S., Belousova, A. V., Smolyuk, L. T., Ulitko, M. V., Uimin, M. A., Byzov, I. V.
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container_end_page 251
container_issue 2
container_start_page 248
container_title Bulletin of experimental biology and medicine
container_volume 162
creator Minin, A. S.
Belousova, A. V.
Smolyuk, L. T.
Ulitko, M. V.
Uimin, M. A.
Byzov, I. V.
description Interactions of bimodal (fluorescent and magnetic) nanoparticles with HeLa cells were studied. The nanoparticles, characterized by high magnetic moment and relaxing capacity, exhibited fluorescence sufficient for their use as labels in confocal microscopy and flow cytometry. Penetration of these nanoparticles into the cell depended on their surface charge: positively charged nanoparticles of this structure penetrated inside, while negatively charged particles were not found in the cells.
doi_str_mv 10.1007/s10517-016-3587-8
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subjects Biological Transport
Biomedical and Life Sciences
Biomedicine
Biotechnologies
Carbon - chemistry
Cell Biology
Cell Membrane Permeability
Cell Survival
Charged particles
Confocal microscopy
Flow Cytometry
Fluorescent Dyes - chemistry
Fluorescent Dyes - metabolism
HeLa Cells
Humans
Internal Medicine
Iron
Iron - chemistry
Laboratory Medicine
Magnetite Nanoparticles - chemistry
Microscopy, Confocal
Nanocomposites
Nanocomposites - chemistry
Nanoparticles
Pathology
Quantum dots
Quantum Dots - chemistry
Quantum Dots - metabolism
Static Electricity
Surface charge
Surface Properties
title Interactions of Bimodal Magnetic and Fluorescent Nanoparticles Based on Carbon Quantum Dots and Iron-Carbon Nanocomposites with Cell Cultures
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