Impaired antiviral response of adenovirus-transformed cell lines supports virus replication

Activation of the innate immune response represents one of the most important cellular mechanisms to limit virus replication and spread in cell culture. Here, we examined the effect of adenoviral gene expression on the antiviral response in adenovirus-transformed cell lines; HEK293, HEK293SF and AGE...

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Veröffentlicht in:	Journal of general virology 2016-02, Vol.97 (2), p.293-298
Hauptverfasser:	Bachmann, Mandy, Breitwieser, Theresa, Lipps, Christoph, Wirth, Dagmar, Jordan, Ingo, Reichl, Udo, Frensing, Timo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - immunology Adenoviridae - physiology Cell Line, Transformed Humans Immune Evasion Immunity, Innate Viral Proteins - biosynthesis Viral Proteins - immunology Virus Replication
Online-Zugang:	Volltext
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