Effect of Sodium Fluoride on the Proliferation and Gene Differential Expression in Human RPMI8226 Cells

Although fluoride is known to reduce the incidence of caries, chronic excessive fluoride exposure can impair human health, even resulting in fluorosis. Now the underlying mechanisms of fluoride-induced toxicity are not fully understood. So, we conducted this study with the purpose of investigating t...

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Veröffentlicht in:	Biological trace element research 2015-09, Vol.167 (1), p.11-17
Hauptverfasser:	He, Hong, Wang, Hongmei, Jiao, Yuguo, Ma, Congli, Zhang, Han, Zhou, Zhou
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis - drug effects Apoptosis - genetics Biochemistry Biomedical and Life Sciences Biotechnology Cell Line, Tumor cell proliferation Cell Proliferation - drug effects Cell Proliferation - genetics Cell Survival - drug effects Cell Survival - genetics cell viability Cells cultured cells Cytotoxicity Dose-Response Relationship, Drug Fluorides fluorosis Gene expression gene expression regulation genes Humans Life Sciences mechanism of action messenger RNA Nutrition Oncology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics RNA, Messenger - metabolism Sodium sodium fluoride Sodium Fluoride - pharmacology Transcriptome - drug effects Transcriptome - genetics
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