Anti-allodynic effect of mangiferin in neuropathic rats: Involvement of nitric oxide-cyclic GMP-ATP sensitive K + channels pathway and serotoninergic system

The neurobiology of neuropathic pain is caused by injury in the central or peripheral nervous system. Recent evidence points out that mangiferin shows anti-nociceptive effect in inflammatory pain. However, its role in inflammatory and neuropathic pain and the possible mechanisms of action are not ye...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2016-11, Vol.150-151, p.190-197
Hauptverfasser:	de Los Monteros-Zuñiga, Antonio Espinosa, Izquierdo, Teresa, Quiñonez-Bastidas, Geovanna Nallely, Rocha-González, Héctor Isaac, Godínez-Chaparro, Beatriz
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cyclic GMP - physiology Female KATP Channels - physiology Methiothepin - pharmacology Naloxone - pharmacology Neuralgia - drug therapy NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide - physiology Piperazines - pharmacology Piperidones - pharmacology Pyridines - pharmacology Rats Rats, Wistar Receptors, Serotonin - physiology Spiro Compounds - pharmacology Xanthones - pharmacology
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