Autonomous assembly of ordered metastable DNA nanoarchitecture and in situ visualizing of intracellular microRNAs

Abstract Facile assembly of intelligent DNA nanoobjects with the ability to exert in situ visualization of intracellular microRNAs (miRNAs) has long been concerned in the fields of DNA nanotechnology and basic medical study. Here, we present a driving primer (DP)-triggered polymerization-mediated me...

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Veröffentlicht in:	Biomaterials 2017-03, Vol.120, p.57-65
Hauptverfasser:	Xu, Jianguo, Wu, Zai-Sheng, Wang, Zhenmeng, Le, Jingqing, Zheng, Tingting, Jia, Lee
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Crystallization - methods Dentistry DNA - chemistry DNA - ultrastructure DNA assembly Fluorescent Dyes Humans MCF-7 Cells Metastable DNA nanoarchitecture MicroRNAs - chemistry MicroRNAs - ultrastructure Microscopy, Fluorescence - methods miRNA-21 Molecular Imaging - methods Nanoparticles - chemistry Nanoparticles - ultrastructure Neoplasms, Experimental - chemistry Neoplasms, Experimental - ultrastructure Polymerization-mediated metastable assembly (PMA) Reproducibility of Results Sensitivity and Specificity
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