Effects of age and caloric restriction in the vascular response of renal arteries to endothelin-1 in rats

Cardiovascular alterations are the most prevalent cause of impaired physiological function in aged individuals with kidney being one the most affected organs. Aging-induced alterations in renal circulation are associated with a decrease in endothelium-derived relaxing factors such as nitric oxide (N...

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Veröffentlicht in:	Experimental gerontology 2017-02, Vol.88, p.32-41
Hauptverfasser:	Amor, Sara, García-Villalón, Angel Luis, Rubio, Carmen, Carrascosa, Jose Ma, Monge, Luis, Fernández, Nuria, Martín-Carro, Beatriz, Granado, Miriam
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - physiology Animals Caloric Restriction Cardiovascular Endothelin-1 Endothelin-1 - metabolism Male Nitric Oxide Synthase Type II - genetics Nitric Oxide Synthase Type II - metabolism Nitric Oxide Synthase Type III - genetics Nitric Oxide Synthase Type III - metabolism Rats Rats, Wistar Renal arteries Renal Artery - physiology RNA, Messenger - metabolism
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