Transfectant mosaic spheroids: a new model for evaluation of tumour cell killing in targeted radiotherapy and experimental gene therapy

Background We describe an in vitro tumour model for targeted radiotherapy and gene therapy that incorporates cell population heterogeneity. Materials and methods Transfectant mosaic spheroids (TMS) and transfected mosaic monolayers (TMM) are composed of two cell populations derived from a single cel...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journal of gene medicine 2002-09, Vol.4 (5), p.567-576
Hauptverfasser:	Boyd, M., Mairs, S. C., Stevenson, K., Livingstone, A., Clark, A. M., Ross, S. C., Mairs, R. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	3-Iodobenzylguanidine - metabolism bystander effects Cell Death - genetics Cell Death - radiation effects Flow Cytometry Gene therapy Genetic Therapy Glioma - genetics Glioma - pathology Glioma - radiotherapy Humans Iodine Radioisotopes - metabolism Iodine Radioisotopes - toxicity Mosaicism - genetics noradrenaline transporter spheroids Spheroids, Cellular targeted radiotherapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!