Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2

[Display omitted] Liver sinusoidal endothelial cells (LSECs) are prominent liver-resident antigen (cross-)presenting cells. LSEC cross-priming of naïve CD8 T cells does not require CD4 T cell help in contrast to priming by dendritic cells (DC) but leads to the formation of memory T cells that is pre...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of hepatology 2017-05, Vol.66 (5), p.978-986
Hauptverfasser:	Wittlich, Michaela, Dudek, Michael, Böttcher, Jan P, Schanz, Oliver, Hegenbarth, Silke, Bopp, Tobias, Schmitt, Edgar, Kurts, Christian, Garbers, Christoph, Rose John, Stefan, Knolle, Percy A, Wohlleber, Dirk
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen presentation Antigen-presenting cells Antigen-Presenting Cells - immunology Antigens CD3 antigen CD4 antigen CD4 T cell help CD4-Positive T-Lymphocytes - immunology CD8 antigen CD8-Positive T-Lymphocytes - immunology Cell activation Cell Communication Cells Cells, Cultured Cross-Priming Dendritic cells Effector cells Endothelial cells Endothelial Cells - immunology Flow cytometry Gastroenterology and Hepatology Granzyme B Granzymes - analysis Helper cells Hepatocytes IL-6 trans-signaling Immune response Immunological memory Interleukin 2 Interleukin 6 Interleukin-2 - physiology Liver Liver - immunology Liver primed T cells LSEC Lymphocytes T Memory cells Mice Mice, Inbred C57BL T cell receptors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!