Maternal–fetal cholesterol transport in the second half of mouse pregnancy does not involve LDL receptor‐related protein 2

Aim LDL receptor‐related protein type 2 (LRP2) is highly expressed on both yolk sac and placenta. Mutations in the corresponding gene are associated with severe birth defects in humans, known as Donnai–Barrow syndrome. We here characterized the contribution of LRP2 and maternal plasma cholesterol av...

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Veröffentlicht in:	Acta Physiologica 2017-08, Vol.220 (4), p.471-485
Hauptverfasser:	Zwier, M. V., Baardman, M. E., Dijk, T. H., Jurdzinski, A., Wisse, L. J., Bloks, V. W., Berger, R. M. F., DeRuiter, M. C., Groen, A. K., Plösch, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cholesterol Cholesterol - metabolism Female fetus lipoprotein Low Density Lipoprotein Receptor-Related Protein-2 - metabolism Maternal-Fetal Exchange - physiology Mice Mice, Mutant Strains placenta Pregnancy transport
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