Assessment of antibiotic prophylaxis adequacy in rectal surgery
Antibiotic prophylaxis is the most suitable tool for preventing surgical site infection (SSI), so the development of guidelines and assessment of its monitoring is essential. In this study protocol compliance of antibiotic prophylaxis in rectal surgery and the effect of its adequacy in terms of pre-...
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| Veröffentlicht in: | Revista española de quimioterapia 2017-02, Vol.30 (1), p.14-18 |
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| creator | Del-Moral-Luque, J A Colás-Ruiz, E Gil-Yonte, P Fernández-Cebrián, J M Villar-Del-Campo, M C Delgado-Iribarren, A Valverde-Cánovas, J F Rodríguez-Caravaca, G |
| description | Antibiotic prophylaxis is the most suitable tool for preventing surgical site infection (SSI), so the development of guidelines and assessment of its monitoring is essential. In this study protocol compliance of antibiotic prophylaxis in rectal surgery and the effect of its adequacy in terms of pre-ention of SSI was assessed.
Prospective cohort study was conducted from 1 January 2009 to 30 December 2015. The degree of compliance with antibiotic prophylaxis and causes of non-compliance in rectal surgery was evaluated. The incidence of SSI was studied after a maximum period of 30 days of incubation. To assess the effect of prophylaxis non-compliance on SSI the relative risk (RR) adjusted with the aid of a logistic regression model was used.
The study covered a total of 244 patients. The patients infected reached 20 cases with a SSI cumulative incidence of 8.2% (CI95%: 4.8-11.6). Antibiotic prophylaxis was indicated in all patients and was administered in 98% of cases, with an overall protocol compliance 92.5%. The principal cause of non-compliance was the choice of antibiotic 55.6% (n=10). The effect of inadequacy of antibiotic prophylaxis on surgical infection was RR=0.58, CI95%: 0.10-4.10 (P>0.05).
Compliance with antibiotic prophylaxis was high. No relationship between the adequacy of prophylaxis and incidence of surgical site infection in rectal surgery was found. |
| format | Article |
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Prospective cohort study was conducted from 1 January 2009 to 30 December 2015. The degree of compliance with antibiotic prophylaxis and causes of non-compliance in rectal surgery was evaluated. The incidence of SSI was studied after a maximum period of 30 days of incubation. To assess the effect of prophylaxis non-compliance on SSI the relative risk (RR) adjusted with the aid of a logistic regression model was used.
The study covered a total of 244 patients. The patients infected reached 20 cases with a SSI cumulative incidence of 8.2% (CI95%: 4.8-11.6). Antibiotic prophylaxis was indicated in all patients and was administered in 98% of cases, with an overall protocol compliance 92.5%. The principal cause of non-compliance was the choice of antibiotic 55.6% (n=10). The effect of inadequacy of antibiotic prophylaxis on surgical infection was RR=0.58, CI95%: 0.10-4.10 (P>0.05).
Compliance with antibiotic prophylaxis was high. No relationship between the adequacy of prophylaxis and incidence of surgical site infection in rectal surgery was found.</description><identifier>EISSN: 1988-9518</identifier><identifier>PMID: 28010057</identifier><language>spa</language><publisher>Spain</publisher><subject>Aged ; Aged, 80 and over ; Anti-Bacterial Agents - therapeutic use ; Antibiotic Prophylaxis - standards ; Cohort Studies ; Digestive System Surgical Procedures - methods ; Female ; Guideline Adherence ; Humans ; Incidence ; Male ; Middle Aged ; Patient Compliance ; Prospective Studies ; Rectum - surgery ; Surgical Wound Infection - prevention & control</subject><ispartof>Revista española de quimioterapia, 2017-02, Vol.30 (1), p.14-18</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28010057$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Del-Moral-Luque, J A</creatorcontrib><creatorcontrib>Colás-Ruiz, E</creatorcontrib><creatorcontrib>Gil-Yonte, P</creatorcontrib><creatorcontrib>Fernández-Cebrián, J M</creatorcontrib><creatorcontrib>Villar-Del-Campo, M C</creatorcontrib><creatorcontrib>Delgado-Iribarren, A</creatorcontrib><creatorcontrib>Valverde-Cánovas, J F</creatorcontrib><creatorcontrib>Rodríguez-Caravaca, G</creatorcontrib><title>Assessment of antibiotic prophylaxis adequacy in rectal surgery</title><title>Revista española de quimioterapia</title><addtitle>Rev Esp Quimioter</addtitle><description>Antibiotic prophylaxis is the most suitable tool for preventing surgical site infection (SSI), so the development of guidelines and assessment of its monitoring is essential. In this study protocol compliance of antibiotic prophylaxis in rectal surgery and the effect of its adequacy in terms of pre-ention of SSI was assessed.
Prospective cohort study was conducted from 1 January 2009 to 30 December 2015. The degree of compliance with antibiotic prophylaxis and causes of non-compliance in rectal surgery was evaluated. The incidence of SSI was studied after a maximum period of 30 days of incubation. To assess the effect of prophylaxis non-compliance on SSI the relative risk (RR) adjusted with the aid of a logistic regression model was used.
The study covered a total of 244 patients. The patients infected reached 20 cases with a SSI cumulative incidence of 8.2% (CI95%: 4.8-11.6). Antibiotic prophylaxis was indicated in all patients and was administered in 98% of cases, with an overall protocol compliance 92.5%. The principal cause of non-compliance was the choice of antibiotic 55.6% (n=10). The effect of inadequacy of antibiotic prophylaxis on surgical infection was RR=0.58, CI95%: 0.10-4.10 (P>0.05).
Compliance with antibiotic prophylaxis was high. No relationship between the adequacy of prophylaxis and incidence of surgical site infection in rectal surgery was found.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotic Prophylaxis - standards</subject><subject>Cohort Studies</subject><subject>Digestive System Surgical Procedures - methods</subject><subject>Female</subject><subject>Guideline Adherence</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Patient Compliance</subject><subject>Prospective Studies</subject><subject>Rectum - surgery</subject><subject>Surgical Wound Infection - prevention & control</subject><issn>1988-9518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j0tLAzEURoMgtrb-BcnSzUCek2QlpfiCghu7HjLJHY3Mq7kz4Px7C9bV2RwO33dF1txZWzjN7YrcIn4zpqRy_IashGWcMW3W5HGHCIgd9BMdGur7KdVpmFKgYx7Gr6X1Pwmpj3CafVho6mmGMPmW4pw_IS9bct34FuHuwg05Pj997F-Lw_vL2353KEau-FRIERUzzHAJZSl4dLEJQXhXxggWpG4C1FGGaKXm2uggvQlSSS2Dqk2tnNyQh7_uedZpBpyqLmGAtvU9DDNW3GphbMmVOKv3F3WuO4jVmFPn81L9n5a_izNSgg</recordid><startdate>201702</startdate><enddate>201702</enddate><creator>Del-Moral-Luque, J A</creator><creator>Colás-Ruiz, E</creator><creator>Gil-Yonte, P</creator><creator>Fernández-Cebrián, J M</creator><creator>Villar-Del-Campo, M C</creator><creator>Delgado-Iribarren, A</creator><creator>Valverde-Cánovas, J F</creator><creator>Rodríguez-Caravaca, G</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201702</creationdate><title>Assessment of antibiotic prophylaxis adequacy in rectal surgery</title><author>Del-Moral-Luque, J A ; Colás-Ruiz, E ; Gil-Yonte, P ; Fernández-Cebrián, J M ; Villar-Del-Campo, M C ; Delgado-Iribarren, A ; Valverde-Cánovas, J F ; Rodríguez-Caravaca, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p141t-32d4070713e6621d9dfcc2a96dde8e35fcebd3cd8351575c3a7c34353c4b7b493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2017</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotic Prophylaxis - standards</topic><topic>Cohort Studies</topic><topic>Digestive System Surgical Procedures - methods</topic><topic>Female</topic><topic>Guideline Adherence</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Patient Compliance</topic><topic>Prospective Studies</topic><topic>Rectum - surgery</topic><topic>Surgical Wound Infection - prevention & control</topic><toplevel>online_resources</toplevel><creatorcontrib>Del-Moral-Luque, J A</creatorcontrib><creatorcontrib>Colás-Ruiz, E</creatorcontrib><creatorcontrib>Gil-Yonte, P</creatorcontrib><creatorcontrib>Fernández-Cebrián, J M</creatorcontrib><creatorcontrib>Villar-Del-Campo, M C</creatorcontrib><creatorcontrib>Delgado-Iribarren, A</creatorcontrib><creatorcontrib>Valverde-Cánovas, J F</creatorcontrib><creatorcontrib>Rodríguez-Caravaca, G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Revista española de quimioterapia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Del-Moral-Luque, J A</au><au>Colás-Ruiz, E</au><au>Gil-Yonte, P</au><au>Fernández-Cebrián, J M</au><au>Villar-Del-Campo, M C</au><au>Delgado-Iribarren, A</au><au>Valverde-Cánovas, J F</au><au>Rodríguez-Caravaca, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of antibiotic prophylaxis adequacy in rectal surgery</atitle><jtitle>Revista española de quimioterapia</jtitle><addtitle>Rev Esp Quimioter</addtitle><date>2017-02</date><risdate>2017</risdate><volume>30</volume><issue>1</issue><spage>14</spage><epage>18</epage><pages>14-18</pages><eissn>1988-9518</eissn><abstract>Antibiotic prophylaxis is the most suitable tool for preventing surgical site infection (SSI), so the development of guidelines and assessment of its monitoring is essential. In this study protocol compliance of antibiotic prophylaxis in rectal surgery and the effect of its adequacy in terms of pre-ention of SSI was assessed.
Prospective cohort study was conducted from 1 January 2009 to 30 December 2015. The degree of compliance with antibiotic prophylaxis and causes of non-compliance in rectal surgery was evaluated. The incidence of SSI was studied after a maximum period of 30 days of incubation. To assess the effect of prophylaxis non-compliance on SSI the relative risk (RR) adjusted with the aid of a logistic regression model was used.
The study covered a total of 244 patients. The patients infected reached 20 cases with a SSI cumulative incidence of 8.2% (CI95%: 4.8-11.6). Antibiotic prophylaxis was indicated in all patients and was administered in 98% of cases, with an overall protocol compliance 92.5%. The principal cause of non-compliance was the choice of antibiotic 55.6% (n=10). The effect of inadequacy of antibiotic prophylaxis on surgical infection was RR=0.58, CI95%: 0.10-4.10 (P>0.05).
Compliance with antibiotic prophylaxis was high. No relationship between the adequacy of prophylaxis and incidence of surgical site infection in rectal surgery was found.</abstract><cop>Spain</cop><pmid>28010057</pmid><tpages>5</tpages></addata></record> |
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| identifier | EISSN: 1988-9518 |
| ispartof | Revista española de quimioterapia, 2017-02, Vol.30 (1), p.14-18 |
| issn | 1988-9518 |
| language | spa |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Aged, 80 and over Anti-Bacterial Agents - therapeutic use Antibiotic Prophylaxis - standards Cohort Studies Digestive System Surgical Procedures - methods Female Guideline Adherence Humans Incidence Male Middle Aged Patient Compliance Prospective Studies Rectum - surgery Surgical Wound Infection - prevention & control |
| title | Assessment of antibiotic prophylaxis adequacy in rectal surgery |
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