MicroRNAs in thyroid development, function and tumorigenesis

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that modulate the vast majority of cellular processes. During development, the correct timing and expression of miRNAs in the tissue differentiation is essential for organogenesis and functionality. In thyroid gland,...

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Veröffentlicht in:	Molecular and cellular endocrinology 2017-11, Vol.456, p.44-50
Hauptverfasser:	Fuziwara, Cesar Seigi, Kimura, Edna Teruko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism DICER Gene Expression Regulation, Neoplastic Goiter - genetics Goiter - metabolism Goiter - physiopathology Humans Iodine - metabolism Iodine metabolism-related genes MicroRNA MicroRNAs - genetics MicroRNAs - metabolism Ribonuclease III - genetics Ribonuclease III - metabolism Signal Transduction Thyroid Thyroid cell differentiation Thyroid Epithelial Cells - metabolism Thyroid Epithelial Cells - pathology Thyroid Gland - metabolism Thyroid Gland - physiopathology Thyroid Hormones - genetics Thyroid Hormones - metabolism Thyroid Neoplasms - genetics Thyroid Neoplasms - metabolism Thyroid Neoplasms - physiopathology Thyroid tumor
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