Adenosine A2A and A2B Receptors Differentially Modulate Keratinocyte Proliferation: Possible Deregulation in Psoriatic Epidermis

Adenosine is a potent regulator of inflammation and immunity, but the role of adenosine receptors in keratinocytes remains controversial. We determined that in addition to A2B receptors, human epidermal keratinocytes also express A2A receptors, although to a lower extent. Through the use of selectiv...

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Veröffentlicht in:Journal of investigative dermatology 2017-01, Vol.137 (1), p.123-131
Hauptverfasser: Andrés, Rosa M., Terencio, María Carmen, Arasa, Jorge, Payá, Miguel, Valcuende-Cavero, Francisca, Navalón, Pedro, Montesinos, María Carmen
Format: Artikel
Sprache:eng
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