Synthesis and immunological evaluation of a low molecular weight saccharide with TLR-4 agonist activity

[Display omitted] The paucity of FDA approved adjuvants renders the synthesis, characterization, and use of new compounds as vaccine adjuvants, a necessity. For this purpose, a novel saccharide analog has been synthesized from glucosamine, pyruvylated galactose and 1,4-cyclohexanediol and its biolog...

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