miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7

Autophagy-related gene 7 (ATG7) and miR-106a play an important role in cancer cell autophagy and apoptosis, but the outcome of ATG7 and miR-106a in colorectal cancer (CRC) still remains not clear. In this study, we found that ATG7 and miR-106a expression were mutually related with cell death and pro...

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Veröffentlicht in:	Medical molecular morphology 2017-06, Vol.50 (2), p.76-85
Hauptverfasser:	Hao, Haibin, Xia, Guangfeng, Wang, Chao, Zhong, Fuping, Liu, Laipeng, Zhang, Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Adenocarcinoma - genetics Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - surgery Aged Anatomy Animals Apoptosis Apoptosis - genetics Autophagy Autophagy-Related Protein 7 - genetics Autophagy-Related Protein 7 - metabolism Base Sequence Cell death Cell Line Cell Line, Tumor Cell lines Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - genetics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Colorectal Neoplasms - surgery Female Gene Expression Regulation, Neoplastic HCT116 Cells HT29 Cells Humans Lymphatic Metastasis Male Medicine Medicine & Public Health Mice Mice, Nude MicroRNAs - genetics MicroRNAs - metabolism Middle Aged Molecular Medicine mRNA Neoplasm Staging Neoplasm Transplantation Original Paper Overexpression Pathology Phagocytosis Prognosis Survival Analysis Tumor cell lines Tumor cells
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