Heat induces interleukin-6 in skeletal muscle cells via TRPV1/PKC/CREB pathways

Interleukin-6 (IL-6) is released from skeletal muscle cells and induced by exercise, heat, catecholamine, glucose, lipopolysaccharide, reactive oxygen species, and inflammation. However, the mechanism that induces release of IL-6 from skeletal muscle cells remains unknown. Thermosensitive transient...

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Veröffentlicht in:	Journal of applied physiology (1985) 2017-03, Vol.122 (3), p.683-694
Hauptverfasser:	Obi, Syotaro, Nakajima, Toshiaki, Hasegawa, Takaaki, Kikuchi, Hironobu, Oguri, Gaku, Takahashi, Masao, Nakamura, Fumitaka, Yamasoba, Tatsuya, Sakuma, Masashi, Toyoda, Shigeru, Tei, Chuwa, Inoue, Teruo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cells, Cultured Cyclic AMP Response Element-Binding Protein - immunology Heat-Shock Response - immunology Hot Temperature Interleukin-6 - immunology Mice Muscle Fibers, Skeletal - immunology Protein Kinase C - immunology Signal Transduction - immunology TRPV Cation Channels - immunology
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