α-Pyrone derivatives, tetra/hexahydroxanthones, and cyclodepsipeptides from two freshwater fungi

[Display omitted] Eighteen (1–18) and seven (1, 4, 6–8, 17 and 18) compounds were isolated from organic extracts of axenic cultures of two freshwater fungi Clohesyomyces sp. and Clohesyomyces aquaticus (Dothideomycetes, Ascomycota), respectively. Compounds 1–12 belong to the α-pyrone class of natura...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2017-01, Vol.25 (2), p.795-804
Hauptverfasser:	El-Elimat, Tamam, Raja, Huzefa A., Day, Cynthia S., McFeeters, Hana, McFeeters, Robert L., Oberlies, Nicholas H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antifungal Agents - chemistry Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Ascomycota - chemistry Ascomycota - metabolism Bacteria - drug effects Bacterial peptidyl-tRNA hydrolase Crystallography, X-Ray Cyclodepsipeptides Depsipeptides - chemistry Depsipeptides - isolation & purification Depsipeptides - pharmacology Dose-Response Relationship, Drug Fresh Water - microbiology Freshwater fungi Fungi - drug effects Microbial Sensitivity Tests Molecular Structure Pyrones - chemistry Pyrones - isolation & purification Pyrones - pharmacology Structure-Activity Relationship Tetrahydroxanthones Xanthones - chemistry Xanthones - isolation & purification Xanthones - pharmacology α-Pyrones
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