Rhodium(I)‐Catalyzed Intermolecular Aza‐[4+3] Cycloaddition of Vinyl Aziridines and Dienes: Atom‐Economical Synthesis of Enantiomerically Enriched Functionalized Azepines

A new synthetic application of vinyl aziridines as N‐containing three‐atom components in a rhodium‐catalyzed [4+3] cycloaddition reaction is described. The reaction proceeds well with various silyl dienol ethers and vinyl aziridines, and enables the efficient synthesis of highly functionalized azepi...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-01, Vol.56 (5), p.1351-1355
Hauptverfasser:	Zhu, Chao‐Ze, Feng, Jian‐Jun, Zhang, Junliang
Format:	Artikel
Sprache:	eng
Schlagworte:	[4+3] cycloaddition Absolute configuration Catalysis chiral azepines chirality transfer Cycloaddition Dienes Enantiomers Ethers Rhodium Selectivity Substrates Synthesis vinyl aziridines
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