Bcl-2 overexpression contributes to laryngeal carcinoma cell survival by forming a complex with Hsp90β

Laryngeal carcinoma (LC) is one of the most common malignant tumors of all head and neck squamous cell carcinomas (HNSCCs). However, the molecular mechanism and genetic basis of the development of LC have not been fully elucidated. To explore the possible mechanism, targeted proteomic analysis was p...

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Veröffentlicht in:	Oncology reports 2017-02, Vol.37 (2), p.849-856
Hauptverfasser:	Li, Sai, Li, Jincheng, Hu, Tian, Zhang, Chuhong, Lv, Xiu, He, Sha, Yan, Hanxing, Tan, Yixi, Wen, Meiling, Lei, Mingsheng, Zuo, Jianhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Bcl-2 Biomarkers, Tumor - metabolism Blotting, Western Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - secondary Care and treatment Cell Proliferation Cluster analysis Development and progression Female Gene expression Genetic aspects Health aspects Heat shock proteins HSP90 Heat-Shock Proteins - metabolism Hsp90β Humans Immunoenzyme Techniques Immunoglobulins Immunoprecipitation Laryngeal cancer Laryngeal Neoplasms - metabolism Laryngeal Neoplasms - pathology laryngocarcinoma cancer Lymphatic Metastasis Lymphatic system Male Medical prognosis Metastasis Middle Aged Molecular weight Neoplasm Staging Prognosis Proteins Proteomics Proto-Oncogene Proteins c-bcl-2 - metabolism Tumor Cells, Cultured Tumor proteins Tumors
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