Paclitaxel–Paclitaxel Prodrug Nanoassembly as a Versatile Nanoplatform for Combinational Cancer Therapy

Recently, nanomedicine without drug carriers has attracted many pharmacists’ attention. A novel paclitaxel–s–s–paclitaxel (PTX–s–s–PTX) conjugate with high drug loading (∼78%, w/w) was synthesized by conjugating paclitaxel to paclitaxel by using disulfide linkage. The conjugate could self-assemble i...

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Veröffentlicht in:	ACS applied materials & interfaces 2016-12, Vol.8 (49), p.33506-33513
Hauptverfasser:	Han, Xiangfei, Chen, Jinling, Jiang, Mengjuan, Zhang, Na, Na, Kexin, Luo, Cong, Zhang, Ruoshi, Sun, Mengchi, Lin, Guimei, Zhang, Rong, Ma, Yan, Liu, Dan, Wang, Yongjun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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