A standardized methanol extract of Eclipta prostrata (L.) L. (Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine model of asthma

Eclipta prostrata (L.) L. (Asteraceae) has been used in Brazilian traditional medicine to treat asthma and other respiratory illnesses. To investigate the effects of different doses of a standardized extract of E. prostrata using a murine model of allergen induced asthma. Balb/c mice were sensitized...

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Veröffentlicht in:	Journal of ethnopharmacology 2017-02, Vol.198, p.226-234
Hauptverfasser:	Morel, Lucas Junqueira de Freitas, Azevedo, Bruna Cestari de, Carmona, Fábio, Contini, Silvia Helena Taleb, Teles, Aristônio Magalhães, Ramalho, Fernando Silva, Bertoni, Bianca Waléria, França, Suzelei de Castro, Borges, Marcos de Carvalho, Pereira, Ana Maria Soares
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway Remodeling - drug effects Allergens - immunology Animals Anti-Asthmatic Agents - administration & dosage Anti-Asthmatic Agents - isolation & purification Anti-Asthmatic Agents - pharmacology Anti-inflammatory Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - pharmacology Asthma Asthma - drug therapy Asthma - immunology Asthma - pathology Brazil Bronchial Hyperreactivity - drug therapy Bronchial Hyperreactivity - immunology Bronchial Hyperreactivity - pathology Bronchoalveolar Lavage Fluid - immunology Cytokines - metabolism Demethylwedelolactone Disease Models, Animal Dose-Response Relationship, Drug Eclipta - chemistry Eclipta prostrate Eosinophils - metabolism Male Medicine, Traditional - methods Mice Mice, Inbred BALB C Oroboside Ovalbumin - immunology Plant Extracts - administration & dosage Plant Extracts - pharmacology Th2 Cells - immunology Wedelolactone
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