Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line

Hypoxia occurs within adipose tissue of obese human and mice. However, its role in adipose tissue regulation is still controversial. We used murine preadipocyte 3T3-L1 cells and hypoxia was induced by using hypoxia mimetic agents, as CoCl2. To study adipocyte differentiation, we evaluated the adipoc...

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Veröffentlicht in:Biochimica et biophysica acta. General subjects 2017-03, Vol.1861 (3), p.673-682
Hauptverfasser: Marques, Ana Patrícia, Rosmaninho-Salgado, Joana, Estrada, Marta, Cortez, Vera, Nobre, Rui Jorge, Cavadas, Cláudia
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Sprache:eng
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