New tools for redox biology: From imaging to manipulation

Redox reactions play a key role in maintaining essential biological processes. Deviations in redox pathways result in the development of various pathologies at cellular and organismal levels. Until recently, studies on transformations in the intracellular redox state have been significantly hampered...

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Veröffentlicht in:	Free radical biology & medicine 2017-08, Vol.109, p.167-188
Hauptverfasser:	Bilan, Dmitry S., Belousov, Vsevolod V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Biosensing Techniques D-aminoacid oxidase Embryonic Development - genetics Fluorescence Resonance Energy Transfer Gene Expression Green Fluorescent Proteins - chemistry Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Humans HyPer Imaging Inflammation Luminescent Proteins - chemistry Luminescent Proteins - genetics Luminescent Proteins - metabolism Models, Molecular Molecular Imaging - methods Molecular Probes - biosynthesis Molecular Probes - chemical synthesis Molecular Probes - metabolism NAD NADH NADPH Oxidation-Reduction Protein Structure, Secondary Reactive Oxygen Species - analysis Reactive Oxygen Species - metabolism Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Redox probes RoGFP
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