Admixture in Latin America
Latin Americans arguably represent the largest recently admixed populations in the world. This reflects a history of massive settlement by immigrants (mostly Europeans and Africans) and their variable admixture with Natives, starting in 1492. This process resulted in the population of Latin America...
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| Veröffentlicht in: | Current opinion in genetics & development 2016-12, Vol.41, p.106-114 |
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| container_title | Current opinion in genetics & development |
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| creator | Adhikari, Kaustubh Mendoza-Revilla, Javier Chacón-Duque, Juan Camilo Fuentes-Guajardo, Macarena Ruiz-Linares, Andrés |
| description | Latin Americans arguably represent the largest recently admixed populations in the world. This reflects a history of massive settlement by immigrants (mostly Europeans and Africans) and their variable admixture with Natives, starting in 1492. This process resulted in the population of Latin America showing an extensive genetic and phenotypic diversity. Here we review how genetic analyses are being applied to examine the demographic history of this population, including patterns of mating, population structure and ancestry. The admixture history of Latin America, and the resulting extensive diversity of the region, represents a natural experiment offering an advantageous setting for genetic association studies. We review how recent analyses in Latin Americans are contributing to elucidating the genetic architecture of human complex traits. |
| doi_str_mv | 10.1016/j.gde.2016.09.003 |
| format | Article |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | African Continental Ancestry Group - genetics European Continental Ancestry Group - genetics Genetics, Population - history Genome, Human History, 15th Century History, 16th Century Human Migration - history Humans Latin America Medical Education |
| title | Admixture in Latin America |
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