Progression of Atypical Extraventricular Neurocytoma to Anaplastic Ganglioglioma

We report a childhood case of thalamic atypical extraventricular neurocytoma that progressed to highly anaplastic ganglioglioma (GG) after eight years of dormancy following subtotal resection and chemotherapy. The neurocytoma displayed immunoreactivity only for synaptophysin, beta-catenin, S-100 and...

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Veröffentlicht in:	Human pathology 2017-01, Vol.59, p.125-130
Hauptverfasser:	Rusiecki, Daniel, RH, Lach, Boleslaw, PhD, Manoranjan, Branavan, Fleming, Adam, MD, Ajani, Olufemi, MD, Singh, Sheila K., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Anaplastic ganglioglioma Anaplastic ganglioneurocytoma Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Biopsy Brain cancer Brain Stem Neoplasms - chemistry Brain Stem Neoplasms - genetics Brain Stem Neoplasms - pathology Brain Stem Neoplasms - therapy Brain tumor Cell Proliferation Cell Transformation, Neoplastic - chemistry Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - pathology Child Cytoplasm Disease Progression Epithelial-mesenchymal transition Extraventricular neurocytoma Fatal Outcome Female Ganglioglioma - chemistry Ganglioglioma - genetics Ganglioglioma - pathology Gangrene Gene expression Humans Immunohistochemistry Infant Magnetic Resonance Imaging Mutation Neoplasm, Residual Neurocytoma - chemistry Neurocytoma - genetics Neurocytoma - pathology Neurocytoma - therapy p53 Pathology Pediatrics Proteins STAT3 Thalamus - chemistry Thalamus - pathology Time Factors Tumors
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