Fosfomycin resistance in Acinetobacter baumannii is mediated by efflux through a major facilitator superfamily (MFS) transporter-AbaF

To decipher the function of A1S_1331, named AbaF (Acinetobacter baumannii Fosfomycin efflux), one of the primary targets of AbsR25, a small RNA of A. baumannii. abaF was cloned in a multicopy plasmid and expressed from its native promoter in an efflux-deficient strain-Escherichia coli KAM32. Drug su...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2017-01, Vol.72 (1), p.68-74
Hauptverfasser:	Sharma, Atin, Sharma, Rajnikant, Bhattacharyya, Tapas, Bhando, Timsy, Pathania, Ranjana
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii - drug effects Acinetobacter baumannii - growth & development Acinetobacter baumannii - metabolism Acinetobacter baumannii - pathogenicity Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Biofilms - growth & development Biological Transport, Active Cloning, Molecular Drug Resistance, Bacterial Fosfomycin - metabolism Fosfomycin - pharmacology Gene Expression Profiling Gene Knockout Techniques Genes, Bacterial Microbial Sensitivity Tests Real-Time Polymerase Chain Reaction Virulence
Online-Zugang:	Volltext
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