Insights into the anti-angiogenic properties of phosphaplatins

Phosphaplatins are platinum-based antitumor compounds that, unlike other clinically utilized platinum drugs (i.e. cisplatin, carboplatin, and oxaliplatin), appear to target proteins rather than DNA. Because of their unique mode of action, phosphaplatins are promising drug candidates for cisplatin-re...

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Veröffentlicht in:	Journal of inorganic biochemistry 2016-11, Vol.164, p.5-16
Hauptverfasser:	Yang, Lu, Moghaddas, Shadi, Dezvareh, Homa, Belkacemi, Louiza, Bark, Steven J., Bose, Rathindra N., Do, Loi H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - chemical synthesis Angiogenesis Inhibitors - chemistry Angiogenesis Inhibitors - pharmacology Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Cell Movement - drug effects fas Receptor - metabolism Human Umbilical Vein Endothelial Cells - metabolism Humans Organoplatinum Compounds - chemical synthesis Organoplatinum Compounds - chemistry Organoplatinum Compounds - pharmacology Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-2 - metabolism
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