Synthesis of Functionalized 3‑Spiro[cyclopropa[a]pyrrolizine]- and 3‑Spiro[3-azabicyclo[3.1.0]hexane]oxindoles from Cyclopropenes and Azomethine Ylides via [3 + 2]-Cycloaddition

3-Spiro­[cyclopropa­[a]­pyrrolizine]- and 3-spiro­[3-aza­bicyclo­[3.1.0]­hexane]­oxindoles were prepared in moderate to high yields via one-pot three-component reactions using substituted isatins, α-amino acids, and cyclopropenes. The key step is an intramolecular [3 + 2]-cycloaddition reaction of a...

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Veröffentlicht in:	Journal of organic chemistry 2017-01, Vol.82 (2), p.959-975
Hauptverfasser:	Filatov, Alexander S, Knyazev, Nickolay A, Molchanov, Alexander P, Panikorovsky, Taras L, Kostikov, Rafael R, Larina, Anna G, Boitsov, Vitali M, Stepakov, Alexander V
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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