Testin is a tumor suppressor in non-small cell lung cancer

The Testin gene was previously identified in the fragile chromosomal region FRA7G at 7q31.2. It has been implicated in several types of cancers including prostate, ovarian, breast and gastric cancer. In the present study, we investigated the function of the candidate tumor-suppressor Testin gene in...

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Veröffentlicht in:	Oncology reports 2017-02, Vol.37 (2), p.1027-1035
Hauptverfasser:	Wang, Ming, Wang, Qian, Peng, Wen-Jia, Hu, Jun-Feng, Wang, Zu-Yi, Liu, Hao, Huang, Li-Nian
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Bone marrow Breast cancer Cancer therapies Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Care and treatment Cell cycle Cell growth Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Cytoskeletal Proteins - genetics Cytoskeletal Proteins - metabolism Development and progression Female Gene expression Gene Expression Regulation, Neoplastic Genes, Tumor Suppressor Genetic aspects Health aspects Humans invasion Kinases LIM Domain Proteins - genetics LIM Domain Proteins - metabolism Lung cancer Lung cancer, Non-small cell Lung Neoplasms - genetics Lung Neoplasms - metabolism Lung Neoplasms - pathology Lymphoma Medical research Metastasis Mice, Inbred BALB C Mortality non-small cell lung cancer proliferation Proteins Studies Testin gene Tumor suppressor genes Xenograft Model Antitumor Assays
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