Does detection of DDX4 mRNA in cell‐free seminal plasma represents a reliable noninvasive germ cell marker in patients with nonobstructive azoospermia?

Summary This study aimed to investigate the potential application of DDX4 gene expression in cell‐free seminal mRNA as a noninvasive biomarker for the identification of the presence of germ cells in men with nonobstructive azoospermia and to correlate this factor with testicular biopsy. Male reprodu...

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Veröffentlicht in:	Andrologia 2017-10, Vol.49 (8), p.e12739-n/a
Hauptverfasser:	Abdallah, W., Hashad, D., Abdelmaksoud, R., Hashad, M. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult azoospermia Azoospermia - genetics Azoospermia - metabolism Azoospermia - pathology Biomarkers - metabolism Biopsy DEAD-box RNA Helicases - genetics DEAD-box RNA Helicases - metabolism Follicle Stimulating Hormone - blood free seminal mRNA Gene expression Germ cells Germ Cells - metabolism Germ Cells - pathology Humans Luteinizing Hormone - blood Male Males marker nonobstructive Polymerase chain reaction Prostate Retrospective Studies Semen Semen - metabolism Semen Analysis Spermatozoa - metabolism Spermatozoa - pathology Testes Testis - pathology Transglutaminases - genetics Transglutaminases - metabolism
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