Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation
The Immune Development in Pediatric Transplantation (IMPACT) study was conducted to evaluate relationships among alloimmunity, protective immunity, immune development, physical parameters, and clinical outcome in children undergoing kidney transplantation. We prospectively evaluated biopsy‐proven ac...
Gespeichert in:
| Veröffentlicht in: | American journal of transplantation 2017-06, Vol.17 (6), p.1549-1562 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1562 |
|---|---|
| container_issue | 6 |
| container_start_page | 1549 |
| container_title | American journal of transplantation |
| container_volume | 17 |
| creator | Ettenger, R. Chin, H. Kesler, K. Bridges, N. Grimm, P. Reed, E. F. Sarwal, M. Sibley, R. Tsai, E. Warshaw, B. Kirk, A. D. |
| description | The Immune Development in Pediatric Transplantation (IMPACT) study was conducted to evaluate relationships among alloimmunity, protective immunity, immune development, physical parameters, and clinical outcome in children undergoing kidney transplantation. We prospectively evaluated biopsy‐proven acute rejection (BPAR), de novo donor‐specific antibody (dnDSA) formation, viremia, viral infection, T cell immunophenotyping, and body mass index (BMI)/weight Z scores in the first year posttransplantation in 106 pediatric kidney transplant recipients. Outcomes were excellent with no deaths and 98% graft survival. Rejection and dnDSAs occurred in 24% and 22%, respectively. Pretransplant cytomegalovirus (CMV) and Epstein–Barr virus (EBV) serologies and subsequent viremia were unrelated to BPAR or dnDSA. Viremia occurred in 73% of children (EBV, 34%; CMV, 23%; BMK viremia, 23%; and JC virus, 21%). Memory lymphocyte phenotype at baseline was not predictive of alloimmune complications. Patients who developed viral infection had lower weight (−2.1) (p = 0.028) and BMI (−1.2) (p = 0.048) Z scores at transplantation. The weight difference persisted to 12 months compared with patients without infection (p = 0.038). These data indicate that there is a high prevalence of viral disease after pediatric kidney transplantation, and underweight status at transplantation appears to be a risk factor for subsequent viral infection. The occurrence of viremia/viral infection is not associated with alloimmune events.
This prospective, multicenter, one‐year study of pediatric kidney transplant recipients from the IMPACT consortium finds that underweight status at transplant is a risk factor for subsequent viral infection and that viral infection is not associated with either biopsy‐proven rejection or generation of donor‐specific antibodies. |
| doi_str_mv | 10.1111/ajt.14169 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1851292707</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1851292707</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3889-f3f8c42fd58d22e9e30fd96873227b5dd76fe6e406f84c63ca54294f68340c3f3</originalsourceid><addsrcrecordid>eNp1kV1rFTEQhoMo9kMv_AMS8Eahpydfm00ul2K1WrTIUfBqSZOJzWE3e5pkkfMj-p_N6am9EJybGZhnXmbmRegVJae0xtKsyykVVOon6JBKQhaSCv70sebNATrKeU0IbZliz9EBa7XShPJDdPcNBlPCFPNN2OBunOIv_CMkGINZ1mwGfBE92B1xgrthmMI4zjGU7Qk20eEvc0lh16zglUlmhAIp4xBxuQF8HlIu-CeYhDtfG_gKXDB1wuLPwUXY4lUyMW8GE8v9Ei_QM2-GDC8f8jH6fv5-dfZxcfn1w8VZd7mwXCm98NwrK5h3jXKMgQZOvNNStZyx9rpxrpUeJAgivRJWcmsawbTwUnFBLPf8GL3d627SdDtDLv0YsoWhLgLTnHuqGso0a0lb0Tf_oOtpTvXeStUXCsK1ZpV6t6dsmnJO4PtNCqNJ256SfudRXz3q7z2q7OsHxfl6BPdI_jWlAss98DsMsP2_Ut99Wu0l_wAGOZxD</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1901403992</pqid></control><display><type>article</type><title>Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation</title><source>MEDLINE</source><source>Wiley Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Ettenger, R. ; Chin, H. ; Kesler, K. ; Bridges, N. ; Grimm, P. ; Reed, E. F. ; Sarwal, M. ; Sibley, R. ; Tsai, E. ; Warshaw, B. ; Kirk, A. D.</creator><creatorcontrib>Ettenger, R. ; Chin, H. ; Kesler, K. ; Bridges, N. ; Grimm, P. ; Reed, E. F. ; Sarwal, M. ; Sibley, R. ; Tsai, E. ; Warshaw, B. ; Kirk, A. D.</creatorcontrib><description>The Immune Development in Pediatric Transplantation (IMPACT) study was conducted to evaluate relationships among alloimmunity, protective immunity, immune development, physical parameters, and clinical outcome in children undergoing kidney transplantation. We prospectively evaluated biopsy‐proven acute rejection (BPAR), de novo donor‐specific antibody (dnDSA) formation, viremia, viral infection, T cell immunophenotyping, and body mass index (BMI)/weight Z scores in the first year posttransplantation in 106 pediatric kidney transplant recipients. Outcomes were excellent with no deaths and 98% graft survival. Rejection and dnDSAs occurred in 24% and 22%, respectively. Pretransplant cytomegalovirus (CMV) and Epstein–Barr virus (EBV) serologies and subsequent viremia were unrelated to BPAR or dnDSA. Viremia occurred in 73% of children (EBV, 34%; CMV, 23%; BMK viremia, 23%; and JC virus, 21%). Memory lymphocyte phenotype at baseline was not predictive of alloimmune complications. Patients who developed viral infection had lower weight (−2.1) (p = 0.028) and BMI (−1.2) (p = 0.048) Z scores at transplantation. The weight difference persisted to 12 months compared with patients without infection (p = 0.038). These data indicate that there is a high prevalence of viral disease after pediatric kidney transplantation, and underweight status at transplantation appears to be a risk factor for subsequent viral infection. The occurrence of viremia/viral infection is not associated with alloimmune events.
This prospective, multicenter, one‐year study of pediatric kidney transplant recipients from the IMPACT consortium finds that underweight status at transplant is a risk factor for subsequent viral infection and that viral infection is not associated with either biopsy‐proven rejection or generation of donor‐specific antibodies.</description><identifier>ISSN: 1600-6135</identifier><identifier>EISSN: 1600-6143</identifier><identifier>DOI: 10.1111/ajt.14169</identifier><identifier>PMID: 27989013</identifier><language>eng</language><publisher>United States: Elsevier Limited</publisher><subject>Adolescent ; Adult ; Autoimmune Diseases - complications ; Biopsy ; Child ; Child Nutrition Disorders - complications ; Child, Preschool ; clinical research/practice ; Cytomegalovirus ; Cytomegalovirus - isolation & purification ; Cytomegalovirus Infections - complications ; Cytomegalovirus Infections - virology ; Epstein-Barr virus ; Epstein-Barr Virus Infections - complications ; Epstein-Barr Virus Infections - virology ; Female ; Follow-Up Studies ; Glomerular Filtration Rate ; Graft Rejection - etiology ; Graft Survival - immunology ; Herpesvirus 4, Human - isolation & purification ; Humans ; Immunology ; Infant ; infection and infectious agents ; Infections ; Interferon ; Kidney Failure, Chronic - surgery ; Kidney Function Tests ; Kidney transplantation ; Kidney Transplantation - adverse effects ; kidney transplantation/nephrology ; Kidney transplants ; Lymphocytes T ; Male ; nutrition ; Nutritional Status ; Pediatrics ; Prognosis ; Prospective Studies ; rejection ; Risk Factors ; translational research/science ; Transplants & implants ; viral ; Viral infections ; Viremia - complications ; Young Adult</subject><ispartof>American journal of transplantation, 2017-06, Vol.17 (6), p.1549-1562</ispartof><rights>2016 The American Society of Transplantation and the American Society of Transplant Surgeons</rights><rights>2016 The American Society of Transplantation and the American Society of Transplant Surgeons.</rights><rights>2017 the American Society of Transplantation and the American Society of Transplant Surgeons</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3889-f3f8c42fd58d22e9e30fd96873227b5dd76fe6e406f84c63ca54294f68340c3f3</citedby><cites>FETCH-LOGICAL-c3889-f3f8c42fd58d22e9e30fd96873227b5dd76fe6e406f84c63ca54294f68340c3f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fajt.14169$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fajt.14169$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27989013$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ettenger, R.</creatorcontrib><creatorcontrib>Chin, H.</creatorcontrib><creatorcontrib>Kesler, K.</creatorcontrib><creatorcontrib>Bridges, N.</creatorcontrib><creatorcontrib>Grimm, P.</creatorcontrib><creatorcontrib>Reed, E. F.</creatorcontrib><creatorcontrib>Sarwal, M.</creatorcontrib><creatorcontrib>Sibley, R.</creatorcontrib><creatorcontrib>Tsai, E.</creatorcontrib><creatorcontrib>Warshaw, B.</creatorcontrib><creatorcontrib>Kirk, A. D.</creatorcontrib><title>Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation</title><title>American journal of transplantation</title><addtitle>Am J Transplant</addtitle><description>The Immune Development in Pediatric Transplantation (IMPACT) study was conducted to evaluate relationships among alloimmunity, protective immunity, immune development, physical parameters, and clinical outcome in children undergoing kidney transplantation. We prospectively evaluated biopsy‐proven acute rejection (BPAR), de novo donor‐specific antibody (dnDSA) formation, viremia, viral infection, T cell immunophenotyping, and body mass index (BMI)/weight Z scores in the first year posttransplantation in 106 pediatric kidney transplant recipients. Outcomes were excellent with no deaths and 98% graft survival. Rejection and dnDSAs occurred in 24% and 22%, respectively. Pretransplant cytomegalovirus (CMV) and Epstein–Barr virus (EBV) serologies and subsequent viremia were unrelated to BPAR or dnDSA. Viremia occurred in 73% of children (EBV, 34%; CMV, 23%; BMK viremia, 23%; and JC virus, 21%). Memory lymphocyte phenotype at baseline was not predictive of alloimmune complications. Patients who developed viral infection had lower weight (−2.1) (p = 0.028) and BMI (−1.2) (p = 0.048) Z scores at transplantation. The weight difference persisted to 12 months compared with patients without infection (p = 0.038). These data indicate that there is a high prevalence of viral disease after pediatric kidney transplantation, and underweight status at transplantation appears to be a risk factor for subsequent viral infection. The occurrence of viremia/viral infection is not associated with alloimmune events.
This prospective, multicenter, one‐year study of pediatric kidney transplant recipients from the IMPACT consortium finds that underweight status at transplant is a risk factor for subsequent viral infection and that viral infection is not associated with either biopsy‐proven rejection or generation of donor‐specific antibodies.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Autoimmune Diseases - complications</subject><subject>Biopsy</subject><subject>Child</subject><subject>Child Nutrition Disorders - complications</subject><subject>Child, Preschool</subject><subject>clinical research/practice</subject><subject>Cytomegalovirus</subject><subject>Cytomegalovirus - isolation & purification</subject><subject>Cytomegalovirus Infections - complications</subject><subject>Cytomegalovirus Infections - virology</subject><subject>Epstein-Barr virus</subject><subject>Epstein-Barr Virus Infections - complications</subject><subject>Epstein-Barr Virus Infections - virology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Glomerular Filtration Rate</subject><subject>Graft Rejection - etiology</subject><subject>Graft Survival - immunology</subject><subject>Herpesvirus 4, Human - isolation & purification</subject><subject>Humans</subject><subject>Immunology</subject><subject>Infant</subject><subject>infection and infectious agents</subject><subject>Infections</subject><subject>Interferon</subject><subject>Kidney Failure, Chronic - surgery</subject><subject>Kidney Function Tests</subject><subject>Kidney transplantation</subject><subject>Kidney Transplantation - adverse effects</subject><subject>kidney transplantation/nephrology</subject><subject>Kidney transplants</subject><subject>Lymphocytes T</subject><subject>Male</subject><subject>nutrition</subject><subject>Nutritional Status</subject><subject>Pediatrics</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>rejection</subject><subject>Risk Factors</subject><subject>translational research/science</subject><subject>Transplants & implants</subject><subject>viral</subject><subject>Viral infections</subject><subject>Viremia - complications</subject><subject>Young Adult</subject><issn>1600-6135</issn><issn>1600-6143</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kV1rFTEQhoMo9kMv_AMS8Eahpydfm00ul2K1WrTIUfBqSZOJzWE3e5pkkfMj-p_N6am9EJybGZhnXmbmRegVJae0xtKsyykVVOon6JBKQhaSCv70sebNATrKeU0IbZliz9EBa7XShPJDdPcNBlPCFPNN2OBunOIv_CMkGINZ1mwGfBE92B1xgrthmMI4zjGU7Qk20eEvc0lh16zglUlmhAIp4xBxuQF8HlIu-CeYhDtfG_gKXDB1wuLPwUXY4lUyMW8GE8v9Ei_QM2-GDC8f8jH6fv5-dfZxcfn1w8VZd7mwXCm98NwrK5h3jXKMgQZOvNNStZyx9rpxrpUeJAgivRJWcmsawbTwUnFBLPf8GL3d627SdDtDLv0YsoWhLgLTnHuqGso0a0lb0Tf_oOtpTvXeStUXCsK1ZpV6t6dsmnJO4PtNCqNJ256SfudRXz3q7z2q7OsHxfl6BPdI_jWlAss98DsMsP2_Ut99Wu0l_wAGOZxD</recordid><startdate>201706</startdate><enddate>201706</enddate><creator>Ettenger, R.</creator><creator>Chin, H.</creator><creator>Kesler, K.</creator><creator>Bridges, N.</creator><creator>Grimm, P.</creator><creator>Reed, E. F.</creator><creator>Sarwal, M.</creator><creator>Sibley, R.</creator><creator>Tsai, E.</creator><creator>Warshaw, B.</creator><creator>Kirk, A. D.</creator><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201706</creationdate><title>Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation</title><author>Ettenger, R. ; Chin, H. ; Kesler, K. ; Bridges, N. ; Grimm, P. ; Reed, E. F. ; Sarwal, M. ; Sibley, R. ; Tsai, E. ; Warshaw, B. ; Kirk, A. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3889-f3f8c42fd58d22e9e30fd96873227b5dd76fe6e406f84c63ca54294f68340c3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Autoimmune Diseases - complications</topic><topic>Biopsy</topic><topic>Child</topic><topic>Child Nutrition Disorders - complications</topic><topic>Child, Preschool</topic><topic>clinical research/practice</topic><topic>Cytomegalovirus</topic><topic>Cytomegalovirus - isolation & purification</topic><topic>Cytomegalovirus Infections - complications</topic><topic>Cytomegalovirus Infections - virology</topic><topic>Epstein-Barr virus</topic><topic>Epstein-Barr Virus Infections - complications</topic><topic>Epstein-Barr Virus Infections - virology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Glomerular Filtration Rate</topic><topic>Graft Rejection - etiology</topic><topic>Graft Survival - immunology</topic><topic>Herpesvirus 4, Human - isolation & purification</topic><topic>Humans</topic><topic>Immunology</topic><topic>Infant</topic><topic>infection and infectious agents</topic><topic>Infections</topic><topic>Interferon</topic><topic>Kidney Failure, Chronic - surgery</topic><topic>Kidney Function Tests</topic><topic>Kidney transplantation</topic><topic>Kidney Transplantation - adverse effects</topic><topic>kidney transplantation/nephrology</topic><topic>Kidney transplants</topic><topic>Lymphocytes T</topic><topic>Male</topic><topic>nutrition</topic><topic>Nutritional Status</topic><topic>Pediatrics</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>rejection</topic><topic>Risk Factors</topic><topic>translational research/science</topic><topic>Transplants & implants</topic><topic>viral</topic><topic>Viral infections</topic><topic>Viremia - complications</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ettenger, R.</creatorcontrib><creatorcontrib>Chin, H.</creatorcontrib><creatorcontrib>Kesler, K.</creatorcontrib><creatorcontrib>Bridges, N.</creatorcontrib><creatorcontrib>Grimm, P.</creatorcontrib><creatorcontrib>Reed, E. F.</creatorcontrib><creatorcontrib>Sarwal, M.</creatorcontrib><creatorcontrib>Sibley, R.</creatorcontrib><creatorcontrib>Tsai, E.</creatorcontrib><creatorcontrib>Warshaw, B.</creatorcontrib><creatorcontrib>Kirk, A. D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ettenger, R.</au><au>Chin, H.</au><au>Kesler, K.</au><au>Bridges, N.</au><au>Grimm, P.</au><au>Reed, E. F.</au><au>Sarwal, M.</au><au>Sibley, R.</au><au>Tsai, E.</au><au>Warshaw, B.</au><au>Kirk, A. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation</atitle><jtitle>American journal of transplantation</jtitle><addtitle>Am J Transplant</addtitle><date>2017-06</date><risdate>2017</risdate><volume>17</volume><issue>6</issue><spage>1549</spage><epage>1562</epage><pages>1549-1562</pages><issn>1600-6135</issn><eissn>1600-6143</eissn><abstract>The Immune Development in Pediatric Transplantation (IMPACT) study was conducted to evaluate relationships among alloimmunity, protective immunity, immune development, physical parameters, and clinical outcome in children undergoing kidney transplantation. We prospectively evaluated biopsy‐proven acute rejection (BPAR), de novo donor‐specific antibody (dnDSA) formation, viremia, viral infection, T cell immunophenotyping, and body mass index (BMI)/weight Z scores in the first year posttransplantation in 106 pediatric kidney transplant recipients. Outcomes were excellent with no deaths and 98% graft survival. Rejection and dnDSAs occurred in 24% and 22%, respectively. Pretransplant cytomegalovirus (CMV) and Epstein–Barr virus (EBV) serologies and subsequent viremia were unrelated to BPAR or dnDSA. Viremia occurred in 73% of children (EBV, 34%; CMV, 23%; BMK viremia, 23%; and JC virus, 21%). Memory lymphocyte phenotype at baseline was not predictive of alloimmune complications. Patients who developed viral infection had lower weight (−2.1) (p = 0.028) and BMI (−1.2) (p = 0.048) Z scores at transplantation. The weight difference persisted to 12 months compared with patients without infection (p = 0.038). These data indicate that there is a high prevalence of viral disease after pediatric kidney transplantation, and underweight status at transplantation appears to be a risk factor for subsequent viral infection. The occurrence of viremia/viral infection is not associated with alloimmune events.
This prospective, multicenter, one‐year study of pediatric kidney transplant recipients from the IMPACT consortium finds that underweight status at transplant is a risk factor for subsequent viral infection and that viral infection is not associated with either biopsy‐proven rejection or generation of donor‐specific antibodies.</abstract><cop>United States</cop><pub>Elsevier Limited</pub><pmid>27989013</pmid><doi>10.1111/ajt.14169</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1600-6135 |
| ispartof | American journal of transplantation, 2017-06, Vol.17 (6), p.1549-1562 |
| issn | 1600-6135 1600-6143 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1851292707 |
| source | MEDLINE; Wiley Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adolescent Adult Autoimmune Diseases - complications Biopsy Child Child Nutrition Disorders - complications Child, Preschool clinical research/practice Cytomegalovirus Cytomegalovirus - isolation & purification Cytomegalovirus Infections - complications Cytomegalovirus Infections - virology Epstein-Barr virus Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - virology Female Follow-Up Studies Glomerular Filtration Rate Graft Rejection - etiology Graft Survival - immunology Herpesvirus 4, Human - isolation & purification Humans Immunology Infant infection and infectious agents Infections Interferon Kidney Failure, Chronic - surgery Kidney Function Tests Kidney transplantation Kidney Transplantation - adverse effects kidney transplantation/nephrology Kidney transplants Lymphocytes T Male nutrition Nutritional Status Pediatrics Prognosis Prospective Studies rejection Risk Factors translational research/science Transplants & implants viral Viral infections Viremia - complications Young Adult |
| title | Relationship Among Viremia/Viral Infection, Alloimmunity, and Nutritional Parameters in the First Year After Pediatric Kidney Transplantation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T17%3A28%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Relationship%20Among%20Viremia/Viral%20Infection,%20Alloimmunity,%20and%20Nutritional%20Parameters%20in%20the%20First%20Year%20After%20Pediatric%20Kidney%20Transplantation&rft.jtitle=American%20journal%20of%20transplantation&rft.au=Ettenger,%20R.&rft.date=2017-06&rft.volume=17&rft.issue=6&rft.spage=1549&rft.epage=1562&rft.pages=1549-1562&rft.issn=1600-6135&rft.eissn=1600-6143&rft_id=info:doi/10.1111/ajt.14169&rft_dat=%3Cproquest_cross%3E1851292707%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1901403992&rft_id=info:pmid/27989013&rfr_iscdi=true |