Hydroxypropylcellulose as matrix carrier for novel cage-like microparticles prepared by spray-freeze-drying technology

•A novel cage-like composite particles used HPC as carrier was developed.•An interesting strategy by means of spray-freeze-drying technique was used.•The spray-freeze-dried CMs exhibited excellent dissolution-enhanced specialty.•HPC was demonstrated to be an effective matrix carrier for drug nanocry...

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Veröffentlicht in:Carbohydrate polymers 2017-02, Vol.157, p.953-961
Hauptverfasser: Wei, Shaofeng, Ma, Yueqin, Luo, Jing, He, Xiaoru, Yue, Pengfei, Guan, Zhiyu, Yang, Ming
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Sprache:eng
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