Molecular and in silico analysis of a new plasmid-mediated AmpC β-lactamase (CMH-2) in clinical isolates of Klebsiella pneumoniae

Two Klebsiella strains isolated from urine samples were positive for blaAmpC by PCR and showed sequence similarity with CMH-1 (98.6%) after sequencing. It also shares 82% similarity with ACT-1, 85% with MIR-1 and 81% with the chromosomal AmpC gene of Enterobacter cloacae. This gene was associated wi...

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Veröffentlicht in:	Infection, genetics and evolution genetics and evolution, 2017-03, Vol.48, p.34-39
Hauptverfasser:	Ingti, Birson, Laskar, Monjur Ahmed, Choudhury, Sudip, Maurya, Anand Prakash, Paul, Deepjyoti, Talukdar, Anupam Das, Choudhury, Manabendra Dutta, Dhar, Debadatta, Chakravarty, Atanu, Bhattacharjee, Amitabha
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacterial Proteins - chemistry Bacterial Proteins - genetics beta-Lactamases - chemistry beta-Lactamases - genetics beta-Lactams - pharmacology Catalytic Domain Computer Simulation Drug Resistance, Bacterial - genetics Humans Klebsiella Infections - microbiology Klebsiella pneumoniae - enzymology Klebsiella pneumoniae - genetics Microbial Sensitivity Tests Models, Molecular
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