5.32 A ZEBRAFISH MODEL FOR IDENTIFYING COMMON BIOLOGICAL MECHANISMS AND PHARMACOLOGICAL PATHWAYS IN AUTISM SPECTRUM DISORDERS

Objectives: The goal of this research is to understand common biological mechanisms underlying ASD. By capitalizing on the advantages of zebrafish as a model organism, our objective is to progress from gene discovery to molecular mechanisms disrupted in ASD and finally to the identification of poten...

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Veröffentlicht in:	Journal of the American Academy of Child and Adolescent Psychiatry 2016-10, Vol.55 (10), p.S194-S194
Hauptverfasser:	Ijaz, Sundas, BS, Ghosh, Marcus, Wilson, Steve, PhD, Rihel, Jason, PhD, Giraldez, Antonio J., PhD, State, Matthew, MD, PhD, Hoffman, Ellen J., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomy Applied behavior analysis Autism Autism Spectrum Disorders Autistic children Behavioral Science Research Body size Central nervous system Circuits CRISPR Danio rerio Discovery Feasibility Forebrain Genes Genetics Hypothalamus Identification Molecular modelling Nervous system Neural networks Neurodevelopmental disorders Neurology Neurons Neuropsychology Pediatrics Psychiatry Psychopharmacology Siblings Technology Zebrafish Zinc Zinc finger proteins
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