A randomized, controlled multicentric study of inhaled budesonide and intravenous methylprednisolone in the treatment on acute exacerbation of chronic obstructive pulmonary disease

Abstract Background Almost all international guidelines recommend corticosteroids for management of exacerbations of chronic obstructive pulmonary disease (COPD), because it leads to improved outcomes of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Nevertheless, due to its...

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Veröffentlicht in:	Respiratory medicine 2016-12, Vol.121, p.39-47
Hauptverfasser:	Ding, Zhen, Li, Xiu, Lu, Youjin, Rong, Guangsheng, Yang, Ruiqing, Zhang, Ruixia, Wang, Guiqin, Wei, Xiqiang, Ye, Yongqing, Qian, Zhaoxia, Liu, Hongyan, Zhu, Daifeng, Zhou, Ruiqing, Zhu, Kun, Ni, Rongping, Xia, Kui, Luo, Nan, Pei, Cong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Administration, Inhalation Aged Bronchodilator Agents - administration & dosage Bronchodilator Agents - therapeutic use Budesonide - administration & dosage Budesonide - therapeutic use Carbon Dioxide - blood Chronic obstructive pulmonary disease Drug dosages Dyspnea Exacerbation Female Forced Expiratory Volume - drug effects Glucocorticoids - administration & dosage Glucocorticoids - therapeutic use Humans Inhaled corticosteroid Injections, Intravenous Male Methylprednisolone - administration & dosage Methylprednisolone - therapeutic use Middle Aged Mortality Oxygen - blood Partial Pressure Pulmonary Disease, Chronic Obstructive - blood Pulmonary Disease, Chronic Obstructive - drug therapy Pulmonary Disease, Chronic Obstructive - physiopathology Pulmonary/Respiratory Single-Blind Method Systemic corticosteroid Ventilation Vital Capacity - drug effects
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