A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca super(2+) Release During Axonal Specification

Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca super(2+), a broad intracellular second messenger, promotes both Rac1 activation and neurite extension. Ca super(2+) release from the endoplasm...

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Veröffentlicht in:The Journal of neuroscience 2016-10, Vol.36 (43), p.11107-11119
Hauptverfasser: Wilson, Carlos, Munoz-Palma, Ernesto, Henriquez, Daniel R, Palmisano, Ilaria, Nunez, M Tulio, Giovanni, Simone Di, Gonzalez-Billault, Christian
Format: Artikel
Sprache:eng
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