A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca super(2+) Release During Axonal Specification
Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca super(2+), a broad intracellular second messenger, promotes both Rac1 activation and neurite extension. Ca super(2+) release from the endoplasm...
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Veröffentlicht in: | The Journal of neuroscience 2016-10, Vol.36 (43), p.11107-11119 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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