European Code against Cancer 4th Edition: Alcohol drinking and cancer
Abstract Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, l...
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| Veröffentlicht in: | Cancer epidemiology 2016-12, Vol.45, p.181-188 |
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| container_title | Cancer epidemiology |
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| creator | Scoccianti, Chiara Cecchini, Michele Anderson, Annie S Berrino, Franco Boutron-Ruault, Marie-Christine Espina, Carolina Key, Timothy J Leitzmann, Michael Norat, Teresa Powers, Hilary Wiseman, Martin Romieu, Isabelle |
| description | Abstract Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%–13%) of all cancer cases in men and 3% (95% CI: 1%–5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: “If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention.” |
| doi_str_mv | 10.1016/j.canep.2016.09.011 |
| format | Article |
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As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%–13%) of all cancer cases in men and 3% (95% CI: 1%–5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: “If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention.”</description><identifier>ISSN: 1877-7821</identifier><identifier>EISSN: 1877-783X</identifier><identifier>DOI: 10.1016/j.canep.2016.09.011</identifier><identifier>PMID: 27816465</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Acetaldehyde ; Alcohol drinking ; Alcohol use ; Beverages ; Cancer ; Cardiovascular disease ; Conflicts of interest ; Disease ; Epidemiology ; Ethanol ; Europe ; Health risk assessment ; Hematology, Oncology and Palliative Medicine ; Internal Medicine ; Primary prevention</subject><ispartof>Cancer epidemiology, 2016-12, Vol.45, p.181-188</ispartof><rights>International Agency for Research on Cancer</rights><rights>2016 International Agency for Research on Cancer</rights><rights>Copyright © 2016 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.</rights><rights>Copyright Elsevier Limited 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c516t-ebbda74cce0ae190fe0c8c85895c64b563a6b4dd3a5f3079d01204816ea870f43</citedby><cites>FETCH-LOGICAL-c516t-ebbda74cce0ae190fe0c8c85895c64b563a6b4dd3a5f3079d01204816ea870f43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1846823917?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,781,785,3551,27928,27929,45999,64389,64391,64393,72473</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27816465$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Scoccianti, Chiara</creatorcontrib><creatorcontrib>Cecchini, Michele</creatorcontrib><creatorcontrib>Anderson, Annie S</creatorcontrib><creatorcontrib>Berrino, Franco</creatorcontrib><creatorcontrib>Boutron-Ruault, Marie-Christine</creatorcontrib><creatorcontrib>Espina, Carolina</creatorcontrib><creatorcontrib>Key, Timothy J</creatorcontrib><creatorcontrib>Leitzmann, Michael</creatorcontrib><creatorcontrib>Norat, Teresa</creatorcontrib><creatorcontrib>Powers, Hilary</creatorcontrib><creatorcontrib>Wiseman, Martin</creatorcontrib><creatorcontrib>Romieu, Isabelle</creatorcontrib><title>European Code against Cancer 4th Edition: Alcohol drinking and cancer</title><title>Cancer epidemiology</title><addtitle>Cancer Epidemiol</addtitle><description>Abstract Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%–13%) of all cancer cases in men and 3% (95% CI: 1%–5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: “If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention.”</description><subject>Acetaldehyde</subject><subject>Alcohol drinking</subject><subject>Alcohol use</subject><subject>Beverages</subject><subject>Cancer</subject><subject>Cardiovascular disease</subject><subject>Conflicts of interest</subject><subject>Disease</subject><subject>Epidemiology</subject><subject>Ethanol</subject><subject>Europe</subject><subject>Health risk assessment</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Internal Medicine</subject><subject>Primary 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cancer</title><author>Scoccianti, Chiara ; Cecchini, Michele ; Anderson, Annie S ; Berrino, Franco ; Boutron-Ruault, Marie-Christine ; Espina, Carolina ; Key, Timothy J ; Leitzmann, Michael ; Norat, Teresa ; Powers, Hilary ; Wiseman, Martin ; Romieu, Isabelle</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c516t-ebbda74cce0ae190fe0c8c85895c64b563a6b4dd3a5f3079d01204816ea870f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Acetaldehyde</topic><topic>Alcohol drinking</topic><topic>Alcohol use</topic><topic>Beverages</topic><topic>Cancer</topic><topic>Cardiovascular disease</topic><topic>Conflicts of interest</topic><topic>Disease</topic><topic>Epidemiology</topic><topic>Ethanol</topic><topic>Europe</topic><topic>Health risk assessment</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Internal Medicine</topic><topic>Primary 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| source | Elsevier ScienceDirect Journals Complete; ProQuest Central UK/Ireland |
| subjects | Acetaldehyde Alcohol drinking Alcohol use Beverages Cancer Cardiovascular disease Conflicts of interest Disease Epidemiology Ethanol Europe Health risk assessment Hematology, Oncology and Palliative Medicine Internal Medicine Primary prevention |
| title | European Code against Cancer 4th Edition: Alcohol drinking and cancer |
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